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Table 1 CPGs characteristics and development methods for recommendations

From: Evaluation of the current guidelines for antibacterial therapy strategies in patients with cirrhosis or liver failure

Guideline, year Region/country Developers Target group Journal Multidiscipli-nary team Grading system Evidence based Guideline review
EASL 2018 [10] Europe EASL Physicians J Hepatol Hepatologists GRADE Systematic literature review Peer review
CMA 2018 [11] China LFALG, CSID; CMA; SLDALG, CSH, CMA Physicians J Clin Hepatol Hepatologists GRADE NR NR
EASL 2017 [12] Europe EASL NR J Hepatol Hepatologists GRADE NR Reviewers
KASL 2017 [13] Korea KASL Physicians Dig Liver Dis KASL Committee GRADE Systematic literature review External review board composed of seven KASL members
CMA 2017 [14] China CSH, CMA Physicians Chin J Gastrointest Endosc Hepatologists GRADE NR NR
NICE 2016 [15] The United Kingdom NICE Physician Hepatologist, Nurse Specialist, Patient/Carer Member, Pharmacist Hepatology GRADE Systematic literature review NR
CMA 2016 [16] China CSH, CMA; CSG, CMA; CSE, CMA Physician J Clin Hepatobiliary Dis Hepatologists GRADE NR NR
JSG 2015 [17] Japan JSG NR J Gastroenterol Hepatologists GRADE Systematic literature review Evaluation Committee
BSG 2015 [18] The United Kingdom Clinical Services and Standards Committee of BSG Clinicians and healthcare professionals Gut Hepatologist, gastroenterologist, Member of BSG liver section, interventional radiologist; patient representative, research nurse; Nursing representative Oxford Systematic literature review External peer reviewer
APASL consensus 2014 [19] Asia APASL NR Hepatol Int Hepatologists Oxford Systematic literature review, expert panel NR
APCCMID 2013 [20] Asia-Pacific The member of APCCMID Clinicians Hepatobiliary Pancreat Dis Int NR GRADE NR NR
AASLD 2012 [21] America AASLD Physicians AASLD Practice Guidelines Committee ACC/AHA Systematic literature review NR
EASL 2010 [22] Europe EASL NR J Hepatol Hepatologists GRADE Systematic literature review, expert opinion Three reviewers
SIGN 2008 [23] Scotland SIGN Acute physicians, gastroenterologists, gastrointestinal surgeons, endoscopists, pharmacists, anaesthetists and nurses Gastroenterologist, Radiologist, Principal Pharmacist, Gastroenterology Nurse Practitioner, Haematologist, Physician SIGN methodology Systematic literature review Specialist review
  1. CPGs clinical practice guidelines, EASL European Association for the Study of the Liver, CMA Chinese Medical Association, LFALG Liver Failure and Artificial Liver Group, CSID Chinese Society of Infectious Diseases, SLDALG Severe Liver Disease and Artificial Liver Group, CSH Chinese Society of Hepatology, KASL The Korean Association for the Study of the Liver, NICE National Institute for Health and Care Excellence, CSG Chinese Society of Gastroenterology, CSE Chinese Society of Endoscopy, JSG Japanese Society of Gastroenterology, BSG the British Society of Gastroenterology, APASL Asian Pacific Association for the Study of the Liver, APCCMID Asia-Pacifc Congress of Clinical Microbiology and Infection Consensus, AASLD The American Association for the Study of Liver Diseases, SIGN Scottish Intercollegiate Guidelines Network, GRADE:Grading of Recommendations Assessment, Development and Evaluation, ACC/AHA the American College of Cardiology and the American Heart Association Practice Guidelines, NR not report