Table 6 Comparing the different blood biomarkers of COVID-19 patients in each MDW quartile

Hematology markers

White blood cell (× 10³ per μL)

1

613

8.056

3.999

0.1615

2.2

33.5

0.403

2

614

7.845

3.6683

0.148

2.1

27.2

3

614

7.883

3.7089

0.1497

2.2

36.8

4

613

8.544

5.0169

0.2026

1.2

39.1

Total

2454

8.082

4.1409

0.0836

1.2

39.1

Platelet (× 10³ per μL)

1

613

240.65

101.408

4.096

77

1015

 < 0.001

2

614

236.4

96.429

3.892

34

980

3

614

223.53

82.662

3.336

10

650

4

613

210.24

84.356

3.407

7

638

Total

2454

227.71

92.27

1.863

7

1015

Neutrophil %

1

613

66.449

12.8279

0.5181

22.5

96

 < 0.001

2

614

67.864

12.6981

0.5125

19.1

94.8

3

614

70.98

11.8736

0.4792

10.6

94

4

613

74.946

13.0348

0.5265

18.4

96.3

Total

2454

70.059

13.0235

0.2629

10.6

96.3

Lymphocyte %

1

613

21.301

10.9329

0.4416

2

57.8

 < 0.001

2

614

19.717

10.5829

0.4271

1.6

62.9

3

614

18.373

10.0544

0.4058

2

87.1

4

613

16.284

10.2825

0.4153

1.1

65.7

Total

2454

18.919

10.6225

0.2144

1.1

87.1

Monocyte %

1

613

10.489

4.0981

0.1655

1.6

26.7

 < 0.001

2

614

10.815

4.2217

0.1704

2.1

43.9

3

614

9.732

4.1094

0.1658

1.6

40.5

4

613

8.019

4.307

0.174

1.4

32.1

Total

2454

9.764

4.3198

0.0872

1.4

43.9

Neutrophil absolute (× 10³ per μL)

1

613

5.628

3.6845

0.1488

0.7

31.4

 < 0.001

2

614

5.569

3.3693

0.136

0.6

25.8

3

614

5.751

3.1023

0.1252

0.6

24.3

4

613

6.697

4.7034

0.19

0.5

35.7

Total

2454

5.911

3.7892

0.0765

0.5

35.7

Lymphocyte absolute (× 10³ per μL)

1

613

1.517

0.8252

0.0333

0.2

6.8

 < 0.001

2

614

1.362

0.6802

0.0275

0.2

4.3

3

614

1.336

1.4619

0.059

0.2

32

4

613

1.164

0.8607

0.0348

0.1

11.7

Total

2454

1.345

1.01

0.0204

0.1

32

Monocyte absolute (× 10³ per μL)

1

613

0.779

0.3538

0.0143

0.2

2.4

 < 0.001

2

614

0.789

0.3908

0.0158

0.2

4.7

3

614

0.723

0.3839

0.0155

0.1

3.7

4

613

0.621

0.4162

0.0168

0

4.4

Total

2454

0.728

0.3923

0.0079

0

4.7

Coagulation markers

Prothrombin time (s)

1

331

14.13

1.456

0.08

11

27

0.403

2

356

14.22

1.461

0.077

12

28

3

397

14.16

2.153

0.108

12

48

4

434

14.64

2.3

0.11

12

32

Total

1518

14.31

1.931

0.05

11

48

APTT (s)

1

327

37.68

4.29

0.237

27

54

 < 0.001

2

348

38.8

6.171

0.331

26

81

3

394

38.6

5.844

0.294

13

107

4

430

40.42

7.542

0.364

27

112

Total

1499

38.97

6.252

0.161

13

112

D-dimer (μg/mL)

1

146

1.1

1.863

0.154

0

14

 < 0.001

2

148

1.14

2.148

0.177

0

18

3

197

0.99

1.146

0.082

0

11

4

238

1.59

2.081

0.135

0

18

Total

729

1.24

1.857

0.069

0

18

Troponin (pg/mL)

1

112

176.49

1515.662

143.217

3

16,051

0.403

2

84

66.21

420.444

45.874

3

3843

3

114

25.1

89.552

8.387

3

928

4

137

54.5

167.589

14.318

3

1408

Total

447

79.77

786.492

37.2

3

16,051

COVID-19 inflammation markers

Ferritin (ng/mL)

1

215

466.13

477.287

32.551

9

2835

 < 0.001

2

234

616.69

773.147

50.542

9

8018

3

280

865.08

793.872

47.443

9

5222

4

318

1265.2

1303.864

73.117

41

13,960

Total

1047

849.17

978.782

30.249

9

13,960

LDH (U/L)

1

267

232.35

88.064

5.389

6

748

 < 0.001

2

300

250.94

100.639

5.81

109

682

3

348

307.09

132.538

7.105

119

1115

4

372

393.51

208.041

10.786

104

2498

Total

1287

303.47

158.832

4.427

6

2498

C-reactive protein (mg/L)

1

557

38.1835

54.85315

2.3242

0.4

384.7

 < 0.001

2

564

48.38

67.75575

2.85303

0.4

509.3

3

578

69.8327

74.31234

3.09099

0.4

418.6

4

577

118.5815

103.7148

4.3177

0.6

569.5

Total

2276

69.1298

83.40931

1.74835

0.4

569.5

Procalcitonin (ng/mL)

1

437

0.31069

2.794236

0.133666

0.02

57.94

0.018

2

456

0.44145

2.449261

0.114697

0.02

32.54

3

487

2.28523

37.79447

1.712631

0.02

831.4

4

507

4.27661

21.36995

0.949073

0.03

256.24

Total

1887

1.91744

22.28269

0.512958

0.02

831.4

Liver enzymes

ALT (U/L)

1

422

37.334

34.9598

1.7018

5

273

 < 0.001

2

454

36.455

30.2239

1.4185

4.7

222

3

471

44.571

66.076

3.0446

3.5

1091

4

508

56.4

127.7525

5.6681

3.2

2666

Total

1855

44.178

78.3383

1.8189

3.2

2666

AST (U/L)

1

75

40.69

48.437

5.593

0

341

 < 0.001

2

86

37.28

40.325

4.348

0

303

3

92

46.93

64.371

6.711

12

592

4

97

165.62

633.57

64.329

1

5808

Total

350

76.12

339.827

18.165

0

5808

Albumin (g/dL)

1

421

4.0435

0.53899

0.02627

1.8

5.4

 < 0.001

2

454

4.0132

0.51224

0.02404

0.8

5

3

469

3.9004

0.52955

0.02445

0.6

5

4

507

3.6516

0.53603

0.02381

1.7

4.8

Total

1851

3.8925

0.55173

0.01282

0.6

5.4

Bilirubin, total (mg/dL)

1

421

0.57

0.434

0.021

0

4

0.403

2

457

0.62

0.631

0.03

0

8

3

471

0.71

1.548

0.071

0

31

4

507

0.77

0.795

0.035

0

8

Total

1856

0.67

0.963

0.022

0

31

Creatinine (mg/dL)

1

569

1.026

3.8608

0.1619

0.2

92.2

 < 0.001

2

558

0.907

1.0408

0.0441

0.1

24.1

3

571

1.284

6.3533

0.2659

0.1

125.9

4

578

1.095

1.0308

0.0429

0.2

10.8

Total

2276

1.079

3.7931

0.0795

0.1

125.9