Skip to main content

Table 4 Prediction accuracy for sepsis mortality risk gained by adding each circulating biomarker to basic model

From: Association of mitochondrial respiratory chain enzymes with the risk and mortality of sepsis among Chinese children

Statistics

Basic Model

Basic Model Plus

CoQ10

Complex I

Complex II + III

Complex II + III

Complex IV

Complex I + III

FoF1-ATPase

CoQ10 and Complex I + III

Calibration

         

 AIC

56.67

44.57

50.70

49.36

49.04

50.49

43.06

49.84

39.96

 BIC

68.14

57.95

64.08

62.74

62.43

63.87

56.44

63.23

55.25

 LR

Ref

14.1

7.97

9.31

9.62

8.18

15.61

8.82

20.71

 LR (P)

Ref

 < 0.001

0.005

0.002

0.002

0.004

 < 0.001

0.003

 < 0.001

Discrimination

         

 NRI

Ref

0.032

0.317

0.083

0.157

0.498

0.046

0.632

0.005

 IDI

Ref

0.003

0.808

0.265

0.575

0.392

0.006

0.377

 < 0.001

 ROC area

0.881

0.932

0.881

0.884

0.893

0.888

0.928

0.903

0.950

 ROC curve P

Ref

0.143

0.389

0.864

0.593

0.731

0.185

0.613

0.047

  1. AIC Akaike information criterion, BIC Bayesian information criterion, LR likelihood ratio, NRI net reclassification improvement, IDI integrated discrimination improvement, ROC Relative operating characteristic curve, Ref. reference group. Basic model included age, gender, Pediatric critical illness score (Day 1), number of multiple organ failure, and shock
Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us