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Table 2 The comparisons of circulating biomarkers between children with sepsis and controls, as well as between survived and deceased in children with sepsis

From: Association of mitochondrial respiratory chain enzymes with the risk and mortality of sepsis among Chinese children

Biomarkers

Controls

Children with sepsis

P1

P2

All

Deceased

Survived

CoQ10 (μmol/L)

1.0 (0.8 to 1.2)

0.7 (0.5 to 1.0)

0.5 (0.4 to 0.6)

0.8 (0.6 to 1.1)

 < 0.001

 < 0.001

Complex I (nmol/min.mg)

107.7 (95.2 to 120.8)

107.1 (98.8 to 124.4)

113.8 (98.5 to 125.0)

106.2 (98.8 to 124.4)

0.460

0.371

Complex II (nmol/min.mg)

99.6 (88.0 to 108.1)

88.2 (78.8 to 100.7)

87.1 (70.1 to 98.5)

91.3 (79.9 to 101.4)

0.004

0.499

Complex II + III (nmol/min.mg)

186.3 (170.2 to 202.7)

184.9 (158.8 to 199.8)

186.8 (132.2 to 207.5)

182.3 (163.6 to 199.6)

0.260

0.606

Complex IV (nmol/min.mg)

136.3 (123.1 to 155.7)

143.6 (88.1 to 166.6)

149.2 (88.8 to 164.1)

132.3 (88.1 to 166.8)

0.521

0.983

Complex I + III (nmol/min.mg)

898.1 (806.9 to 1083.1)

622.8 (384.7 to 811.9)

236.8 (132.6 to 592.5)

731.7 (563.4 to 823.4)

 < 0.001

 < 0.001

FoF1-ATPase (nmol/min.mg)

751.9 (605 to 903.3)

356.6 (222.8 to 544.7)

383.9 (215.3 to 710.8)

335.2 (222.8 to 535.1)

 < 0.001

0.486

  1. P values are calculated by t-test for normal variables and nonparametric Wilcoxon rank sum tests for non-normal data expressed as median (interquartile range). P1: Children with sepsis versus controls; P2: Survived versus deceased
  2. CoQ10 Coenzyme Q10