Table 4 Clinical variables comparison between 30-day survivors and non-survivors among sepsis cases (non-infectious organ failure excluded)
Variables | All septic patients (n = 278) | Survivors (n = 204) | Non-survivors (n = 74) | p value |
|---|---|---|---|---|
Age, median (IQR) | 77 (64–84) | 77 (64–83) | 78 (65–85) | 0.210 |
Male, n (%) | 162 (58) | 120 (59) | 42 (57) | 0.757 |
Charlson comorbidity index | 4 (3–5) | 3 (3–5) | 5 (4–6) | 0.157 |
Site of infection, n (%) | ||||
 Respiratory | 165 (59) | 119 (58) | 46 (62) | 0.658 |
 Genitourinary | 68 (24) | 48 (24) | 20 (27) | 0.412 |
 Gastrointestinal | 27 (10) | 20 (10) | 7 (9) | 0.348 |
 Others | 28 (10) | 21 (10) | 7 (9) | 0.316 |
Septic shock, n (%) |  | 85 (42) | 52 (70) | < 0.001 |
APACHE II score, median (IQR) | 28 (24–33) | 27 (22–31) | 31 (26–37) | < 0.001 |
SOFA score, median (IQR) | 9 (6–11) | 8 (6–10) | 11 (9–12) | < 0.001 |
NEWS, median (IQR) | 11 (9–13) | 10 (9–12) | 12 (10–14) | 0.002 |
MEWS, median (IQR) | 6 (5–7) | 6 (5–7) | 6 (5–9) | 0.043 |
WBC (× 109/L), median (IQR) | 11.68 (7.65–18.07) | 11.91 (8.38–19.66) | 10.76 (5.06–15.75) | 0.009 |
CRP (mg/L), median (IQR) | 9.09 (3.87–17.34) | 8.69 (3.57–17.07) | 10.75 (4.80–19.04) | 0.270 |
Procalcitonin (ng/mL), median (IQR) | 1.74 (0.51–8.51) | 1.61 (0.47–8.95) | 2.06 (0.62–7.22) | 0.666 |
Presepsin (pg/mL), median (IQR) | 934 (512–1802) | 815 (460–1678) | 1142 (650–2039) | < 0.001 |
Creatinine (mg/dL), median (IQR) | 1.5 (1.0–2.5) | 1.4 (0.9–2.6) | 1.7 (1.0–2.2) | 0.627 |
Bilirubin (mg/dL), median (IQR) | 0.7 (0.4–1.2) | 0.6 (0.4–1.0) | 1.0 (0.5–1.7) | < 0.001 |
Platelet (× 1000/μL), median (IQR) | 197 (115–288) | 206 (141–305) | 145 (63–212) | < 0.001 |
Lactate (mmol/L), median (IQR) | 3.1 (1.9–6.6) | 2.6 (1.6–5.2) | 6.0 (2.9–9.9) |  < 0.001 |