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Table 4 Clinical variables comparison between 30-day survivors and non-survivors among sepsis cases (non-infectious organ failure excluded)

From: Diagnostic and prognostic value of presepsin and procalcitonin in non-infectious organ failure, sepsis, and septic shock: a prospective observational study according to the Sepsis-3 definitions

Variables All septic patients (n = 278) Survivors (n = 204) Non-survivors (n = 74) p value
Age, median (IQR) 77 (64–84) 77 (64–83) 78 (65–85) 0.210
Male, n (%) 162 (58) 120 (59) 42 (57) 0.757
Charlson comorbidity index 4 (3–5) 3 (3–5) 5 (4–6) 0.157
Site of infection, n (%)
 Respiratory 165 (59) 119 (58) 46 (62) 0.658
 Genitourinary 68 (24) 48 (24) 20 (27) 0.412
 Gastrointestinal 27 (10) 20 (10) 7 (9) 0.348
 Others 28 (10) 21 (10) 7 (9) 0.316
Septic shock, n (%)   85 (42) 52 (70) < 0.001
APACHE II score, median (IQR) 28 (24–33) 27 (22–31) 31 (26–37) < 0.001
SOFA score, median (IQR) 9 (6–11) 8 (6–10) 11 (9–12) < 0.001
NEWS, median (IQR) 11 (9–13) 10 (9–12) 12 (10–14) 0.002
MEWS, median (IQR) 6 (5–7) 6 (5–7) 6 (5–9) 0.043
WBC (× 109/L), median (IQR) 11.68 (7.65–18.07) 11.91 (8.38–19.66) 10.76 (5.06–15.75) 0.009
CRP (mg/L), median (IQR) 9.09 (3.87–17.34) 8.69 (3.57–17.07) 10.75 (4.80–19.04) 0.270
Procalcitonin (ng/mL), median (IQR) 1.74 (0.51–8.51) 1.61 (0.47–8.95) 2.06 (0.62–7.22) 0.666
Presepsin (pg/mL), median (IQR) 934 (512–1802) 815 (460–1678) 1142 (650–2039) < 0.001
Creatinine (mg/dL), median (IQR) 1.5 (1.0–2.5) 1.4 (0.9–2.6) 1.7 (1.0–2.2) 0.627
Bilirubin (mg/dL), median (IQR) 0.7 (0.4–1.2) 0.6 (0.4–1.0) 1.0 (0.5–1.7) < 0.001
Platelet (× 1000/μL), median (IQR) 197 (115–288) 206 (141–305) 145 (63–212) < 0.001
Lactate (mmol/L), median (IQR) 3.1 (1.9–6.6) 2.6 (1.6–5.2) 6.0 (2.9–9.9)  < 0.001
  1. IQR interquartile range, APACHE Acute Physiology and Chronic Health Evaluation, SOFA sepsis-related organ failure assessment, NEWS National Early Warning Score, MEWS Modified Early Warning Score, WBC white blood cell, CRP C-reactive protein