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Table 3 Multivariate analysis

From: Safety and clinical outcomes of remdesivir in hospitalised COVID-19 patients: a retrospective analysis of active surveillance database

Variables

Odds ratio

95% Confidence interval

p-value

Adjusted odds ratio

95% Confidence interval

p-value

Age group (years)

 20–40

1.00

     

 40–60

1.51

(0.78, 2.94)

0.222

   

 ≥ 60

2.99

(1.56, 5.73)

0.001

   

Gender

 Male

1.54

(0.99, 2.40)

0.062

   

 Female

1.00

     

Co-morbidities

 Hypertension (Yes/No)

0.71

(0.45, 1.13)

0.146

   

 Diabetes (Yes/No)

1.93

(1.36, 2.75)

0.000

1.55

(1 01, 2.39)

0.05

 Lung disease (Yes/No)

1.85

(0.96, 3.56)

0.063

   

 Cardiac (Yes/No)

2.57

(1.52, 4.33)

0.000

3.76

(1.95, 7.25)

< 0.001

Type of oxygen support

 SLFO

1.00

     

 HFO

2.74

(1.55, 4.83)

0.000

2.35

(1.26, 4.32)

0.007

 NIV

10.37

(6.29, 17.10)

0.000

11.04

(6.4, 18.9)

< 0.001

 MV

36.25

(20.14, 65.23)

0.000

40.51

(21.010, 77.7)

< 0.001

Remdesivir treatment duration

 < 5 days

1

     

 5 days

0.28

(0.19, 0.41)

< 0.001

0.29

(0.19, 0.45)

< 0.001

 ≥ 6 days

0.39

(0.21, 0.72)

0.002

0.40

(0.20, 0.80)

0.009

Concomitant medications

 Steroids

1

     

 Others

1.08

(0.69, 1.69)

0.735

   
  1. SLFO standard low-flow oxygen, HFO high-flow oxygen, NIV non-invasive ventilation, MV mechanical ventilation