Table 3 Hepatitis A clinical outcomes and evidence of acute liver injury
Adult patients | ||||
|---|---|---|---|---|
Evidence of acute liver injury | All patients (N = 212) | Uncomplicated hepatitis (n = 180, 84.9%) | Complicated hepatitis A (n = 29, 13.7%) | Deceased (n = 3, 1.4%) |
INR ≥ 1.5 | 12 (5.6%) | 9 (5.0%) | 0 (0.0%) | 3 (100.0%) |
ALT > 40 U/L | 199 (93.9%) | 168 (93.3%) | 27 (93.1%) | 3 (100.0%) |
AST > 40 U/L | 197 (92.9%) | 168 (93.3%) | 26 (89.7%) | 3 (100.0%) |
ALP > 128 U/L | 192 (90.6%) | 165 (91.7%) | 24 (82.8%) | 3 (100.0%) |
Total bilirubin > 21 U/L | 188 (88.7%) | 160 (88.9%) | 25 (86.2%) | 3 (100.0%) |
Paediatric patients | ||||
|---|---|---|---|---|
Evidence of acute liver injury | All patients (N = 239) | Uncomplicated hepatitis (n = 211, 88.3%) | Complicated hepatitis A (n = 27, 12.8%) | Deceased (n = 1, 0.4%) |
INR 1.50–1.99 | 9 (3.8%) | 8 (3.8%) | 1 (3.7%) | 0 (0.0%) |
INR ≥ 2.0 | 4 (1.7%) | 0 (0.0%) | 3 (11.1%) | 1 (100.0%) |
ALT > 40 U/L | 239 (100.0%) | 211 (100.0%) | 27 (100.0%) | 1 (100.0%) |
AST > 40 U/L | 238 (99.6%) | 211 (100.0%) | 26 (96.3%) | 1 (100.0%) |
ALP > 128 U/L | 233 (97.5%) | 207 (98.1%) | 25 (92.6%) | 1 (100.0%) |
Total bilirubin > 21 U/L | 232 (97.1%) | 206 (97.6%) | 25 (92.6%) | 1 (100.0%) |