From: Immunological effects of convalescent plasma therapy for coronavirus: a scoping review
Responses to CP therapy | Sub categories | Number of studies/(%) | |
---|---|---|---|
Clinical symptoms | Fever/cough | Improvement | 29/5 |
NC/NS | 1/1 | ||
Chest | Improvement | 45 | |
NC/NS | 2 | ||
SOFA | Improvement | 4 | |
NC/NS | 3 | ||
PaO2/FiO2, SaO2 | Improvement | 53 | |
NC/NS | 6 | ||
O2 withdraw, ARDS resolution, Ventilation support | Improvement | 26 | |
NC/NS/need | 8 | ||
Inflammatory response | IL-6 level | Decrease | 16 |
NC/NS Increase | 11 | ||
CRP level | Decrease | 55 | |
NC/NS Increase | 10 | ||
Ferritin | Decrease | 14 | |
NC/NS Increase | 10 | ||
D-dimer | Decrease | 13 | |
NC/NS Increase | 7 | ||
LDH | Decrease | 10 | |
NC/NS Increase | 6 | ||
Immunologic response | Antibody response | Increase | 37 |
NC/NS | 7 | ||
Lymphocyte | Increase | 28 | |
NC/NS | 6 | ||
T cell response | – | 3 | |
Antiviral response (Load of virus) | Decrease | 60 | |
NC/NS Remained positive | 11 |