Table.3 The infectivity, prepatent period and parasitemia measurements in healthy volunteers in malaria sporozoite challenge participated as controls in vaccine or drug trials and in infectivity studies

PfNF54

PfSPZ challenge

100(4/4)

11.7*

7.8

19.55–28.756

[5]

PfNF54

PfSPZ challenge

100(13/13)

11**

[26]

PfNF54

PfSPZ challenge

100 (5/5)

12.7*

10.3

25.6

[71]

PfNF54

PfSPZ challenge

100(6/6)

11.4/12.2*

6.8

[69]

PfNF54

PfSPZ challenge

84(5/6)

13/12.7/13*

10.6/10.3/ 9.9

0.07/0.2

[46]

PfNF54

PfSPZ challenge

100 (28/28)

12.6/11.8/12/ 16.4/13.3/11.9 **

[67]

PfNF54

PfSPZ challenge

100(18/18)

12.5/13/12**

0.5

[27]

PfNF54

PfSPZ challenge

92/91

15.4/13.5**

12.6 /11.1

0.11/0.16

[9]

PfNF54

PfSPZ challenge

100(6/6)

12.7**

[66]

PfNF54

Mosquito bite/PfSPZ

100(6/6)

8.3–9.4**

 ≥ 0.25

[14]

PfNF54

PfSPZ challenge

100(9/9)

11.2*

[68]

PfNF54

PfSPZ challenge

64%(7/11)

56(5/9)

16.9/19.1*

[72]

PfNF54

Mosquito bite

100(5/5)

13.5**

7

[54]

Pf3D7

Mosquito bite

100(12/12)

[37]

PfNF54

Mosquito bite

100(6/6)

11.2*

7.5

33.712

[53]

Pf

Mosquito bite

100(15/15)

11.34/ 12.54*

7/6.38

23.92/35.74

[13]

PfNF54

Mosquito bite

100(13/13)

11.2*

–

–

[78]

PfNF54

Mosquito bite

94.4(17/18)

10.9*

7.5

[45]

PfNF54

Mosquito bite

100(19/19)

10.9*

7.5

1.7

[52]

PfNF54

Mosquito bite

100(6/6)

9**

6.7

[30]

Pf3D7

Mosquito bite

100(6/6)

9–13

[79]

PfNF54

Mosquito bite

100(4/4)

9–18

[15]

PfNF54

Mosquito bite

100(4/4)

8.5**

6.3

 > 0.035

[23]

Pf3D7

Mosquito bite

100(6/6)

9–13

2.7

[16]

Pf3D7

Mosquito bite

100(6/6)

12.8*

[80]

PfNF54

Mosquito bite

100(5/5)

9.2*

[20]

PfNF54

Mosquito bite

100(4/4)

12.5 *

10.8

[17]

Pf3D7

Mosquito bite

100(6/6)

12.3*

[31]

Pf3D7

Mosquito bite

100

10.7

[38]

Pf3D7

Mosquito bite

100(5/5)

11*

 > 1

[56]

Pf3D7

Mosquito bite

100(6/6)

11.6 *

10.8

 > 1

[57]

PfNF54

Mosquito bite

80 (4/5)

7–12

[24]

Pf3D7

Mosquito bite

100 (6/6)

12.9*

[81]

Pf3D7

Mosquito bite

100(5/5)

11.8 *

[55]

Pf3D7

Mosquito bite

100% (6/6)

11–13*

[34]

Pf3D7

Mosquito bite

95(22/23)

12

[36]

Pf3D7

Mosquito bite

100(5/5)

12.3*

9

[21]

Pf3D7

Mosquito bite

100(6/6)

9–12*

7

[51]

Pf

Mosquito bite

100(6/6)

11.8*

11.1

 > 1

[58]

Pf3D7

Mosquito bite

100(6/6)

10.8

[35]

Pf3D7

Mosquito bite

100(16/16)

–

 > 0.5

[82]

Pf3D7

Mosquito bite

100(11/11)

12.25

**

7.4

 > 0.5

[41]

Pf3D7/7G8

Mosquito bite

100(4/4)

10–12

[39]

Pf3D7

Mosquito bite

100(36/36)

11–14

[18]

Pf3D7

Mosquito bite

100(11/11)

11–14

[42]

Pf3D7

Mosquito bite

100 (13/13)

13*

[41]

PfNF54/3D7

Mosquito bite

100 (5/5)

11–14

[33]

Pf7G8

Mosquito bite

100(4/4)

9–12

[49]

Pf

Mosquito bite

100(36/36)

10.8/11.8*

[32]

Pf3D7

Mosquito bite

100(6/6)

10.3**

7.5

 > 0.5

[67]

Pf

Mosquito bite

91(11/12)

7–13

[28]

Pf3D7/Pf7G8

Mosquito bite

100(22/22)

10.9/11.6/11.9**

[29]

PfNF54/NF166.C8/ NF135.C10

Mosquito bite

100(23/23)

10.2/7.2/7.4*

7.5/6.5/6.5

[47]

PfNF135.C10

Mosquito bite

100 (5/5/)

8.5**

-

 > 0.05

[25]

PfNF54/NF166.C8/ NF135.C10

Mosquito bite

100(15/15)

-

-

 > 0.1

[22]

NF166.C8/ NF135.C10

Mosquito bite

100(4/4/)

7.5**

-

 > 0.5

[48]

Pv

Mosquito bite

100(17/17)

12 *

-

[62]

Pv

Mosquito bite

94(15/16)

12.5/12.8 *

9.2–9.4

17.5

[64]

Pv

Mosquito bite

100(2/2)

12–13*

8–11

12.5–1050

[19]

Pv

Mosquito bite

100

11–13

–

–

[83]

Pv

Mosquito bite

94.4(17/18)

11*

9–13

[44]

PV

Mosquito bite

100(6/6)

10.7**

[65]

PV

Mosquito bite

100(18/18)

11, 11, 9 *

[63]