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Table 1 Numbers needed to demonstrate an improvement in viral load monitoring, for different assumptions regarding clinic size and effect sizes

From: Optimised electronic patient records to improve clinical monitoring of HIV-positive patients in rural South Africa (MONART trial): study protocol for a cluster-randomised trial

Number of clinics per arm

Number of patients per clinic1

Coefficient of variation (k)

% with VL suppressed in control

% with VL suppressed in intervention

Power (%)

5

100

0.20

45

67

71

5

100

0.20

45

70

80

5

100

0.20

50

74

71

5

100

0.20

50

77

80

5

100

0.20

55

80

70

5

100

0.20

55

84

80

5

150

0.20

45

66

70

5

150

0.20

45

69

80

5

150

0.20

50

73

70

5

150

0.20

50

77

80

5

150

0.20

55

80

70

5

150

0.20

55

84

80

  1. 1Harmonic mean to account for varying facility size