|
Characteristics
|
Health control
|
HBV carrier
|
Chronic hepatitis B
|
P value
|
|---|
|
Patients
|
24
|
64
|
55
| |
|
Age
| | | | |
|
Mean ± SD
|
46.0 ± 12.3
|
41.2 ± 11.8
|
40.6 ± 11.4
|
0.143
|
|
Media (Range)
|
44 (23–67)
|
41 (16–65)
|
41 (18–64)
|
0.183
|
|
Gender (%)
|
|
Male
|
10 (41.7%)
|
38 (59.4%)
|
39 (70.9%)
|
0.047
|
|
Female
|
14 (58.3%)
|
26 (40.6%)
|
16 (29.1%)
|
|
HBeAg (%)a
|
|
Positive
| |
22 (34.4%)
|
38 (74.5%)
|
< 0.001
|
|
Negative
| |
42 (65.6%)
|
13 (25.5%)
|
|
HBV-DNA (log10 copies/ml)
| |
4.4 ± 2.5
|
6.1 ± 1.9
|
< 0.001
|
|
Mean ± SD
|
|
ALT (U/L)
| |
22.9 (16.1–35.5)
|
91.7 (68.1–184.1)
|
< 0.001
|
|
Media (Range)
|
|
AST (U/L)
| |
23.1 (19.8–31.0)
|
70.1 (45.9–103.8)
|
< 0.001
|
|
Media (Range)
|
|
γ-GT (U/L)
| |
17.8 (12.3–27.8)
|
50.0 (26.2–82.3)
|
< 0.001
|
|
Median (Range)
| |
|
ALP 9U/L)
| |
68.5 (56.6–81.8)
|
72.2 (60.3–89.7)
|
< 0.001
|
|
Media (Range)
| |
|
Albumin (g/L)
| |
44.9 (42.1–46.5)
|
41.7 (39.9–44.6)
|
< 0.001
|
|
Mean ± SD
| |
- HBeAg, hepatitis B e antigen; ALT, alanine amino transferase; AST, aspartate amino transferase; γ-GT, γ-glutamyl transpeptidase; ALP, alkaline phosphatase
- aData for 4 patients were not available
