Skip to main content

Table 4 Factors associated with Immune response

From: Immune response to hepatitis B vaccine following complete immunization of children attending two regional hospitals in the Southwest region of Cameroon: a cross sectional study

Factor All participants Na (%) Adequate immune response nb (%) P value
Male 68 (42.2) 66 (97.1) 0.750
Younger age (6 months) 79 (49.1) 79 (100) 0.001
Mother attaining secondary Education 95 (59) 94 (98.9) 0.356
Born to Chronic HBVc carrier 12 (7.5) 12 (100) 0.548
Received HBVc vaccine at Birth 12 (7.5) 12 (100) 0.548
Received HBIGd at birth 4 (2.5) 4 (100) 0.438
Born at term 149 (92.5) 146 (98) 0.643
Normal Birthweight 138 (85.7) 134 (97.1) 0.710
Neonatal Infection 18 (11.2) 18 (100) 0.472
Documented febrile illnesses 47 (29.2) 47 (100) 0.193
Mother HIV positive 6 (3.7) 6 (100) 0.690
Adequate weight for height for age 139 (86.3) 135 (97.1) 0.723
Duration since last vaccine dose > 3 months 82 (50.9) 80 (97.4) 0.029f
Follows EPIe strictly 131 (81.4) 128 (97.7) 0.741
  1. Bold values represent statistically significant association of variable with anti-HBs
  2. aN total number of infants in a particular group. bn number of infants with adequate immune response within a particular group. cHBV hepatitis b virus. dHBIG hepatitis b immunoglobulin. eEPI expanded program on immunization. fRelational analysis between duration since last dosage and anti HBs titre: Spearman’s Rho (R = −0.172; P = 0.029)