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Table 4 Factors associated with Immune response

From: Immune response to hepatitis B vaccine following complete immunization of children attending two regional hospitals in the Southwest region of Cameroon: a cross sectional study

Factor

All participants Na (%)

Adequate immune response nb (%)

P value

Male

68 (42.2)

66 (97.1)

0.750

Younger age (6 months)

79 (49.1)

79 (100)

0.001

Mother attaining secondary Education

95 (59)

94 (98.9)

0.356

Born to Chronic HBVc carrier

12 (7.5)

12 (100)

0.548

Received HBVc vaccine at Birth

12 (7.5)

12 (100)

0.548

Received HBIGd at birth

4 (2.5)

4 (100)

0.438

Born at term

149 (92.5)

146 (98)

0.643

Normal Birthweight

138 (85.7)

134 (97.1)

0.710

Neonatal Infection

18 (11.2)

18 (100)

0.472

Documented febrile illnesses

47 (29.2)

47 (100)

0.193

Mother HIV positive

6 (3.7)

6 (100)

0.690

Adequate weight for height for age

139 (86.3)

135 (97.1)

0.723

Duration since last vaccine dose > 3 months

82 (50.9)

80 (97.4)

0.029f

Follows EPIe strictly

131 (81.4)

128 (97.7)

0.741

  1. Bold values represent statistically significant association of variable with anti-HBs
  2. aN total number of infants in a particular group. bn number of infants with adequate immune response within a particular group. cHBV hepatitis b virus. dHBIG hepatitis b immunoglobulin. eEPI expanded program on immunization. fRelational analysis between duration since last dosage and anti HBs titre: Spearman’s Rho (R = −0.172; P = 0.029)