Table 1 Demographic and clinical characteristics of patients with bacteremia due to Streptococcus bovis/Streptococcus equinus complex
Characteristics | S. gallolyticus subsp. pasteurianus (n = 29) | S. gallolyticus subsp. gallolyticus (n = 5) | S. lutetiensis (n = 4) | S. infantarius subsp. infantarius (n = 1) | Total (n = 39) | P value SGSP vs. SGSG |
|---|---|---|---|---|---|---|
Age, median (range) | 74 (28–92) | 81 (69–83) | 82 (77–92) | 91 | 76 (28–92) | 0.39 |
Gender, men (%) | 18 (62) | 4 (80) | 3 (75) | 0 (0) | 25 (64) | 0.63 |
Pregnant women | 1 (3) | 0 (0) | 0 (0) | 0 (0) | 1 (3) | 1 |
Co-morbidities | Â | Â | Â | Â | Â | Â |
 Diabetes mellitus | 7 (24) | 0 (0) | 1 (25) | 0 (0) | 8 (21) | 0.56 |
 Liver cirrhosis | 2 (7) | 0 (0) | 0 (0) | 0 (0) | 2 (5) | 1 |
 Chronic kidney disease | 1 (3) | 1 (20) | 1 (25) | 1 (100) | 4 (10) | 0.28 |
 Neutropenia at culture | 3 (10) | 0 (0) | 0 (0) | 0 (0) | 3 (8) | 1 |
 Gastrointestinal surgery within 30 days | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 |
Malignancies | Â | Â | Â | Â | Â | Â |
 Overall malignancies | 16 (55) | 4 (80) | 1 (25) | 0 (0) | 21 (54) | 0.38 |
Gastrointestinal tract | Â | Â | Â | Â | Â | Â |
 Esophageal | 3 (10) | 0 (0) | 0 (0) | 0 (0) | 3 (8) | 1 |
 Stomach | 1 (3) | 1 (20) | 0 (0) | 0 (0) | 2 (5) | 0.28 |
 Colon/rectum | 4 (14) | 3 (60) | 1 (25) | 0 (0) | 8 (21) | 0.048 |
 Bile duct | 3 (10) | 0 (0) | 0 (0) | 0 (0) | 3 (8) | 1 |
 Liver | 1 (3) | 0 (0) | 0 (0) | 0 (0) | 1 (3) | 1 |
Other malignancies | Â | Â | Â | Â | Â | Â |
 Hematologic | 4 (14) | 1 (20) | 0 (0) | 0 (0) | 5 (13) | 1 |
 Brain | 1 (3) | 0 (0) | 0 (0) | 0 (0) | 1 (3) | 1 |
 Oral cavity | 3 (10) | 0 (0) | 0 (0) | 0 (0) | 3 (8) | 1 |
 Prostate | 2 (7) | 0 (0) | 0 (0) | 0 (0) | 2 (5) | 1 |
 Ovary | 2 (7) | 0 (0) | 0 (0) | 0 (0) | 2 (5) | 1 |
 Multiple malignancies (> 1) | 7 (24) | 1 (20) | 0 (0) | 0 (0) | 8 (21) | 1 |
 Known before the bacteremia | 13 (45) | 1 (20) | 1 (25) | 0 (0) | 15 (38) | 0.38 |
 Discovered after the bacteremia | 3 (10) | 3 (60) | 0 (0) | 0 (0) | 6 (15) | 0.029 |
 Colon/rectum | 2 (7) | 3 (60) | 0 (0) | 0 (0) | 5 (13) | 0.015 |
 Bile duct | 1 (3) | 0 (0) | 0 (0) | 0 (0) | 1 (3) | 1 |
Colorectal cancer | Â | Â | Â | Â | Â | Â |
 Known before the bacteremia | 2 (7) | 0 (0) | 1 (25) | 0 (0) | 3 (8) | 1 |
 Discovered after the bacteremia | 2 (7) | 3 (60) | 0 (0) | 0 (0) | 5 (13) | 0.015 |
 Endoscopic examination performed following the bacteremia | 10 (34) | 3 (60) | 2 (50) | 1 (100) | 16 (41) | 0.35 |
Source of bacteremia | Â | Â | Â | Â | Â | Â |
 Primary bacteremia | 10 (34) | 1 (20) | 2 (50) | 1 (100) | 14 (36) | 1 |
 Infective endocarditis | 7 (24) | 2 (40) | 1 (25) | 0 (0) | 10 (26) | 0.59 |
 Biliary tract infection | 6 (21) | 2 (40) | 1 (25) | 0 (0) | 9 (23) | 0.57 |
 Urinary tract infection | 2 (7) | 0 (0) | 0 (0) | 0 (0) | 2 (5) | 1 |
 Others | 4 (14) | 0 (0) | 0 (0) | 0 (0) | 4 (10) | 1 |
Infective endocarditis | Â | Â | Â | Â | Â | Â |
 TTE performed following the bacteremia | 16 (55) | 2 (40) | 3 (75) | 0 (0) | 21 (54) | 0.65 |
 TEE performed following the bacteremia | 0 (0) | 2 (40) | 1 (25) | 0 (0) | 3 (8) | 0.018 |
Computed tomography | 27 (93) | 5 (100) | 4 (100) | 1 (100) | 37 (95) | 1 |
Polymicrobial bacteremia | 6 (21) | 0 (0) | 1 (25) | 0 (0) | 7 (18) | 0.56 |
Escherichia coli | 3 (10) | 0 (0) | 0 (0) | 0 (0) | 3 (8) | 1 |
Klebsiella pneumoniae | 1 (3) | 0 (0) | 0 (0) | 0 (0) | 1 (3) | 1 |
Corynebacterium jeikeium | 1 (3) | 0 (0) | 1 (25) | 0 (0) | 2 (5) | 1 |
Streptococcus pneumoniae | 1 (3) | 0 (0) | 0 (0) | 0 (0) | 1 (3) | 1 |
Thirty-day all-cause mortality | 5 (17) | 0 (0) | 0 (0) | 0 (0) | 5 (13) | 1 |