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Table 6 Baseline characteristics of the patients with IPD (meningitis cases and non-meningitis cases) receiving appropriate/inappropriate antibiotic prescription

From: Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study

  Meningitis cases
n = 314
Non-meningitis cases
n = 492
  Appropriate therapy
n = 114
Inappropriate therapy
n = 200
p Appropriate therapy
n = 331
Inappropriate therapy
n = 161
p
Median age, years (interquartile range) 1.1 (0.6–3.6) 1.1 (0.5–3.2) 0.733 1.5 (0.9–3.1) 1.8 (1.0–3.1) 0.075
Male 69 (60.5) 123 (61.5) 0.865 202 (61.0) 97 (60.2) 0.868
Underlying disease 7 (6.1) 23 (11.5) 0.120 27 (8.2) 44 (27.3) 0.000
ICU admission 35 (30.7) 108 (54.0) 0.000 41 (12.4) 57 (35.4) 0.000
Tracheal intubation 9 (7.9) 59 (29.5) 0.000 14 (4.2) 30 (18.6) 0.000
Death 9 (7.9) 53 (26.5) 0.000 14 (4.2) 16 (9.9) 0.013
Spn not susceptible to penicillin 95 (83.3) 135 (67.5) 0.002 125 (60.5) 56 (32.3) 0.056