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Table 3 Empiric antibiotics therapy of 781 patients with IPD from different regions of China

From: Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study

  All Patients
n = 781
North
n = 349
East
n = 158
South
n = 236
Northwest
n = 38
p*
Penicillins monotherapy 64 (8.2) 18 (5.2) 23 (14.6) 21 (8.9) 2 (5.3) 0.006
Cephalosporin monotherapy 427 (54.7) 199 (57.0) 78 (49.4) 131 (55.5) 19 (50.0) 0.396
Carbapenem monotherapy 90 (11.5) 43 (12.3) 17 (10.8) 25 (10.6) 5 (13.2) 0.895
Cephalosporin plus vancomycin 52 (6.7) 25 (7.2) 7 (4.4) 18 (7.6) 2 (5.3) 0.566
Carbapenem plus vancomycin 122 (15.6) 47 (13.5) 29 (18.4) 36 (15.3) 10 (26.3) 0.142
Cephalosporin plus linezolid 5 (0.6) 4 (1.1) 0 (0) 1 (0.4) 0 (0) 0.278
Carbapenem plus linezolid 7 (0.9) 5 (1.4) 1 (0.6) 1 (0.4) 0 (0) 0.475
Cephalosporin plus teicoplanin 3 (0.4) 3 (0.9) 0 (0) 0 (0) 0 (0) 0.183
Macrolides monotherapy 11 (1.4) 5 (1.4) 3 (1.9) 3 (1.3) 0 (0) 0.715
  1. *All the four regions of China were compared