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Table 3 Empiric antibiotics therapy of 781 patients with IPD from different regions of China

From: Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study

 

All Patients

n = 781

North

n = 349

East

n = 158

South

n = 236

Northwest

n = 38

p*

Penicillins monotherapy

64 (8.2)

18 (5.2)

23 (14.6)

21 (8.9)

2 (5.3)

0.006

Cephalosporin monotherapy

427 (54.7)

199 (57.0)

78 (49.4)

131 (55.5)

19 (50.0)

0.396

Carbapenem monotherapy

90 (11.5)

43 (12.3)

17 (10.8)

25 (10.6)

5 (13.2)

0.895

Cephalosporin plus vancomycin

52 (6.7)

25 (7.2)

7 (4.4)

18 (7.6)

2 (5.3)

0.566

Carbapenem plus vancomycin

122 (15.6)

47 (13.5)

29 (18.4)

36 (15.3)

10 (26.3)

0.142

Cephalosporin plus linezolid

5 (0.6)

4 (1.1)

0 (0)

1 (0.4)

0 (0)

0.278

Carbapenem plus linezolid

7 (0.9)

5 (1.4)

1 (0.6)

1 (0.4)

0 (0)

0.475

Cephalosporin plus teicoplanin

3 (0.4)

3 (0.9)

0 (0)

0 (0)

0 (0)

0.183

Macrolides monotherapy

11 (1.4)

5 (1.4)

3 (1.9)

3 (1.3)

0 (0)

0.715

  1. *All the four regions of China were compared