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Table 3 Factors associated with positive IGRA results

From: Decreased annual risk of tuberculosis infection in South Korean healthcare workers using interferon-gamma release assay between 1986 and 2005

 

IGRA

Total

Univariable

Multivariable

 

Negative

Positive

OR

95% CI

p

OR

95% CI

p

Age

N (%)

N (%)

 

1.096

1.086

1.107

 < 0.001

    

 20–29

780 (93.4)

55 (6.6)

835

1

   

1

   

 30–39

774 (85.6)

130 (14.4)

904

2.259

1.612

3.166

 < 0.001

2.25

1.593

3.18

 < 0.001

 40–49

656 (65.7)

343 (34.3)

999

7.031

5.165

9.570

 < 0.001

5.95

4.282

8.268

0.0028

 50–59

220 (49.0)

229 (51.0)

449

14.013

10.023

19.591

 < 0.001

10.24

7.136

14.692

 < 0.001

 ≥ 60

23 (50.0)

23 (50.0)

46

13.340

7.021

25.345

 < 0.001

13.3

6.637

26.655

 < 0.001

Gender, male

576/2453 (23.5)

308/779 (39.5)

884 (27.4)

2.299

1.931

2.737

 < 0.001

1.56

1.243

1.968

 < 0.001

Finding of CXR

          

 No active lung

2319 (75.0)

774 (25.0)

3093

1

   

1

   

 Healed TB

14 (33.3)

28 (66.7)

42

6.240

3.268

11.915

 < 0.001

4.39

2.175

8.86

 < 0.001

Occupation

          

 Administrative

212 (53.0)

188 (47.0)

400

1

   

1

   

 Techniciana

155 (70.1)

66 (29.9)

221

0.473

0.334

0.671

0.6059

0.703

0.482

1.024

0.8625

 Health-Aidsb

642 (73.9)

227 (26.1)

869

0.447

0.348

0.575

0.9207

0.858

0.648

1.135

0.0454

 Physician

212 (73.6)

76 (26.4)

288

0.403

0.290

0.561

0.4081

0.485

0.334

0.703

0.0040

 Nurse

1232 (84.7)

223 (15.3)

1455

0.202

0.158

0.258

 < 0.001

0.66

0.484

0.899

0.3822

Department

          

 High-riskc

521 (85.7)

87 (14.3)

608

0.443

0.348

0.566

 < .0001

0.895

0.676

1.184

0.436

 Others

1932 (73.6)

693 (26.4)

2625

1

   

1

   

Working duration, months

           

 < 12 months

326 (90.6)

34 (9.4)

360

1

       

 12 to < 60 months

655 (90.7)

67 (9.3)

722

0.956

0.612

1.493

 < .0001

    

 60 to < 120 months

236 (84.6)

43 (15.4)

279

1.675

1.027

2.733

0.0127

    

 120 to < 240 months

531 (79.6)

136 (20.4)

667

2.342

1.551

3.535

0.7556

    

 240 to < 360 months

583 (60.0)

389 (40.0)

972

6.116

4.152

9.010

 < 0.001

    

 > 360 months

119 (51.7)

111 (48.3)

230

8.612

5.500

13.485

 < 0.001

    
  1. Data are presented as numbers (percentages) unless otherwise indicated
  2. HCW health care worker; LTBI latent tuberculous infection; BMI body mass index; TB tuberculosis; CXR chest X-ray; IGRA IFN-γ release assay; IQR interquartile range; CI confidence interval
  3. aTechnicians who perform radiological, laboratory and pathology testing
  4. bEmployees who provide physiotherapy and patient transfer services
  5. chigh risk department defined as those who are working at TB-related departments, such as respiratory department of ward and outpatient clinic, medical intensive care unit, emergency department, microbiology laboratory, and radiology department