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Table 3 Baseline demographic data and clinical characteristics of patients included in the PSM analysis

From: The effect of dobutamine in sepsis: a propensity score matched analysis

Covariate

Original patients (after matching)

Non-dobutamine group (N = 334)

Dobutamine group (N = 118)

P value

Age (years)

70.93 ± 19.89

68.48 ± 16.53

0.231

Gender (Male), n (%)

204 (61.1%)

71 (60.2%)

0.862

Height(cm)

168.78 ± 10.80

168.48 ± 9.70

0.787

Weight (kg)

82.08 ± 26.41

83.06 ± 22.16

0.719

BMI (kg/m2)

28.75 ± 8.59

29.10 ± 6.80

0.683

Temperature (℃)

37.63 ± 1.16

37.88. ± 1.12

0.044

MAP (mmHg)

47.38 ± 15.37

46.46 ± 15.69

0.579

HR (beats min−1)

115.41 ± 23.62

118.93 ± 23.28

0.163

RR (min−1)

30.69 ± 7.56

31.75 ± 8.09

0.199

SOFA score

9.66 ± 3.93

9.87 ± 3.73

0.606

SOFA-cardiovascular score

3.13 ± 1.25

3.21 ± 1.20

0.517

SAPS-I score

24.50 ± 5.69

24.83 ± 5.63

0.590

SAPS-II score

56.55 ± 16.63

56.39 ± 14.87

0.925

ECI

11.00 ± 7.47

11.21 ± 7.91

0.797

Norepinephrine dose (mg)

64.97 ± 90.54

75.78 ± 89.60

0.289

Norepinephrine use

305 (91.3%)

107 (90.7%)

0.833

Urine volume (ml, 1st day)

1169.60 ± 1123.08

1096.28 ± 1011.60

0.534

Input volume (ml, 1st day)

9500.05 ± 7096.23

9488.29 ± 7257.87

0.988

Microbiology, n (%)

 Positive (%)

275 (82.6%)

96 (81.4%)

0.764

 Negative

58 (17.4%)

22(18.6%)

Interventions, n (%)

 Renal replacement use (1st day)

41 (12.3%)

14 (11.9%)

0.907

 Mechanical ventilation use (1st day)

244 (73.1%)

92 (78.0%)

0.294

Comorbidities, n (%)

 Congestive heart failure

204 (61.1%)

73 (61.9%)

0.880

 Pulmonary circulation disease

21 (6.3%)

10 (8.5%)

0.419

 Renal failure

77 (23.1%)

22 (18.6%)

0.319

 Diabetes

112 (33.5%)

43 (36.4%)

0.567

 COPD

81 (24.3%)

33 (28.0%)

0.424

 Coagulopathy

137 (41.0%)

51 (43.2%)

0.676

 Fluid electrolyte disorder

166 (49.7%)

66 (55.9%)

0.244

Admission type, n (%)

 Emergency

310 (92.8%)

110 (93.2%)

0.883

 Elective

24 (7.2%)

8 (6.8%)

Sepsis type, n (%)

 Sepsis

18 (5.4%)

7 (5.9%)

0.913

 Severe sepsis

143 (42.8%)

48 (40.7%)

 Septic shock

173 (51.8%)

63 (53.4%)

Laboratory tests

 Lactate (mmol/L)

3.01 ± 2.56

3.55 ± 2.49

0.047

 Glucose-min

104.74 ± 40.59

108.08 ± 48.52

0.466

 Glucose-max

211.77 ± 112.57

225.84 ± 93.33

0.224

  1. Data are mean ± SD, median (interquartile) or n (%). SOFA Sequential Organ Failure Assessment, ranging from 0 to 24, with higher scores indicating a greater degree of organ failure, ECI Elixhauser comorbidity index, and we used the modified vanWalraven Elixhauser comorbidity score in our study, which consists of 30 comorbidity diseases, range from -19 to 89 points, with higher scores indicating a greater risk of hospital mortality, MAP mean arterial pressure, HR heart rate, RR respiratory rate, SAPS-I simplified acute physiologic score-I; SAPS-II simplified acute physiologic score-II, ICU intensive care unit, COPD chronic obstructive pulmonary disease. The definitions and diagnositic criteria for sepsis, severe sepsis and septic shock were made according to the Surviving Sepsis Campaign Guidelines [1, 13, 14]. No variable had a missing value