From: The effect of dobutamine in sepsis: a propensity score matched analysis
Covariate | Original patients (after matching) | ||
---|---|---|---|
Non-dobutamine group (N = 334) | Dobutamine group (N = 118) | P value | |
Age (years) | 70.93 ± 19.89 | 68.48 ± 16.53 | 0.231 |
Gender (Male), n (%) | 204 (61.1%) | 71 (60.2%) | 0.862 |
Height(cm) | 168.78 ± 10.80 | 168.48 ± 9.70 | 0.787 |
Weight (kg) | 82.08 ± 26.41 | 83.06 ± 22.16 | 0.719 |
BMI (kg/m2) | 28.75 ± 8.59 | 29.10 ± 6.80 | 0.683 |
Temperature (℃) | 37.63 ± 1.16 | 37.88. ± 1.12 | 0.044 |
MAP (mmHg) | 47.38 ± 15.37 | 46.46 ± 15.69 | 0.579 |
HR (beats min−1) | 115.41 ± 23.62 | 118.93 ± 23.28 | 0.163 |
RR (min−1) | 30.69 ± 7.56 | 31.75 ± 8.09 | 0.199 |
SOFA score | 9.66 ± 3.93 | 9.87 ± 3.73 | 0.606 |
SOFA-cardiovascular score | 3.13 ± 1.25 | 3.21 ± 1.20 | 0.517 |
SAPS-I score | 24.50 ± 5.69 | 24.83 ± 5.63 | 0.590 |
SAPS-II score | 56.55 ± 16.63 | 56.39 ± 14.87 | 0.925 |
ECI | 11.00 ± 7.47 | 11.21 ± 7.91 | 0.797 |
Norepinephrine dose (mg) | 64.97 ± 90.54 | 75.78 ± 89.60 | 0.289 |
Norepinephrine use | 305 (91.3%) | 107 (90.7%) | 0.833 |
Urine volume (ml, 1st day) | 1169.60 ± 1123.08 | 1096.28 ± 1011.60 | 0.534 |
Input volume (ml, 1st day) | 9500.05 ± 7096.23 | 9488.29 ± 7257.87 | 0.988 |
Microbiology, n (%) | |||
 Positive (%) | 275 (82.6%) | 96 (81.4%) | 0.764 |
 Negative | 58 (17.4%) | 22(18.6%) | |
Interventions, n (%) | |||
 Renal replacement use (1st day) | 41 (12.3%) | 14 (11.9%) | 0.907 |
 Mechanical ventilation use (1st day) | 244 (73.1%) | 92 (78.0%) | 0.294 |
Comorbidities, n (%) | |||
 Congestive heart failure | 204 (61.1%) | 73 (61.9%) | 0.880 |
 Pulmonary circulation disease | 21 (6.3%) | 10 (8.5%) | 0.419 |
 Renal failure | 77 (23.1%) | 22 (18.6%) | 0.319 |
 Diabetes | 112 (33.5%) | 43 (36.4%) | 0.567 |
 COPD | 81 (24.3%) | 33 (28.0%) | 0.424 |
 Coagulopathy | 137 (41.0%) | 51 (43.2%) | 0.676 |
 Fluid electrolyte disorder | 166 (49.7%) | 66 (55.9%) | 0.244 |
Admission type, n (%) | |||
 Emergency | 310 (92.8%) | 110 (93.2%) | 0.883 |
 Elective | 24 (7.2%) | 8 (6.8%) | |
Sepsis type, n (%) | |||
 Sepsis | 18 (5.4%) | 7 (5.9%) | 0.913 |
 Severe sepsis | 143 (42.8%) | 48 (40.7%) | |
 Septic shock | 173 (51.8%) | 63 (53.4%) | |
Laboratory tests | |||
 Lactate (mmol/L) | 3.01 ± 2.56 | 3.55 ± 2.49 | 0.047 |
 Glucose-min | 104.74 ± 40.59 | 108.08 ± 48.52 | 0.466 |
 Glucose-max | 211.77 ± 112.57 | 225.84 ± 93.33 | 0.224 |