Fig. 1

Serial positron emission tomography with integrated computed tomography images showing response to lung metastases before and after pembrolizumzb treatment, interruption and rechallenge during and after anti-tuberculosis (TB) therapy. a Multiple bilateral lung metastases before pembrolizumab treatment. b Marked reduction in size and number of lung metastases after pembrolizumab treatment. c Enlarging lung metastases after pembrolizumab interruption due to TB reactivation. d Tumour shrinkage after re-challenge with pembrolizumab