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Table 3 Regression analysis for the outcomes after PS matching

From: The impact of early target attainment of vancomycin in critically ill patients with confirmed Gram-positive infection: A retrospective cohort study

Outcomes Early Late P-value Hazard ratio (95%CI) P-value$
30-day mortality, n (%) 22 (23.2) 25 (26.6) 0.5846^^ 2.54 (1.24, 5.22) 0.01
     Odds ratio (95%CI) P-value$*
Developing of vancomycin resistance organism (s) (e.g. (VRSA, VISA), n (%) 3 (2.9) 3 (2.9) 0.9905** 4.28 (0.47, 38.8) 0.19
Eradication of microorganism within 4–5 days of vancomycin initiation, n (%) 72 (69.2) 70 (66.7) 0.6913^^ 1.49 (0.75, 2.96) 0.25
Vancomycin induced acute kidney injury, n (%) 13 (12.5) 19 (18.1) 0.2614^^ 2.59 (1.01, 6.65) 0.04
     Beta coefficient (Estimates) (95%CI) P-value $**
ICU length of stay (Days), Median (Q1, Q3) & 15.0 (9.00, 27.00) 13.0 (4.00, 24.00) 0.1802^ − 0.27 (− 0.58, 0.05) 0.10
Hospital length of stay (Days), Median (Q1, Q3) & 26.0 (14.00, 42.00) 24.0 (15.00, 44.00) 0.8722^ 0.10 (− 0.22, 0.43) 0.54
  1. ^ Wilcoxon rank sum test is used to calculate the P-value
  2. ^^Chi-square test is used to calculate the P-value
  3. **Fisher Exact test is used to calculate the P-value
  4. &Denominator is patients who survived
  5. $Cox proportional hazards regression analysis is used to calculate hazard ratio (HR) and p-value
  6. $*Multivariate logistic regression analysis is used to calculate Odds ratio and p-value
  7. $**Generalized linear model is used to calculate beta coefficient (estimates) and p-value