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Table 3 Identification by ITS sequencing

From: Molecular detection, not extended culture incubation, contributes to diagnosis of fungal infection

Patient history Clinical indication for fungal culture Specimen Direct microscopic examination Identification by ITS sequencing
Acute myeloid leukemia (AML) Disseminated fungal infection involving multiple organs Apical mass, liver biopsy, pericardium Positive Saccaromyces cerevisiae
Recent history of pneumonia requiring hospitalization Left cerebellar lesion on imaging Brain tissue Positive Blastomyces dermatitidis
Heart transplantation Cavitary pneumonia BAL Negative Rhizopus microsporus
Renal transplantation Multiloculted cystic lesion medial to transplanted kidney in left pelvis Blood Negative Histoplasma capsulatum
Hydrocephalus with a ventriculoperitoneal shunt Brain lesion Brain tissue Positive Rhodotorula spp.
Renal transplantation Cavitary lung lesions/pulmonary nodule CSF Negative Aspergillus
AML Pneumonia, sinusitis and periorbital cellulitis Ethmoid Negative Fusarium spp.
Stage III Wilms tumor Skin lesion Scalp lesion Positive Rhizopus spp.
AML Cutaneous fungal lesions Skin biopsy Positive Fusarium spp.
Pregnancy Severe amniotic fluid infection Placenta tissue Positive Candida glabrata
AML Neutropenic fevers and pulmonary nodules Tissue Negative Aspergillus spp.
AML Disseminated fungal infection with empyema, pericarditis Pericardial abscess Positive Candida tropicalis
Renal transplantation Pulmonary cavitary lesion TISC-left upper lobe region Negative Cunningmahella spp.
No significant medical history Liver abscess Liver biopsy Positive Candida lusitaniae
Renal transplantation Disseminated invasive Aspergillosis involving multiple organs Brain tissue Positive Aspergillus spp.
Renal transplantation Mass in the left sinus invading the orbit Eye tissue Negative Aspergillus spp.