From: Molecular detection, not extended culture incubation, contributes to diagnosis of fungal infection
Patient history | Clinical indication for fungal culture | Specimen | Direct microscopic examination | Identification by ITS sequencing |
---|---|---|---|---|
Acute myeloid leukemia (AML) | Disseminated fungal infection involving multiple organs | Apical mass, liver biopsy, pericardium | Positive | Saccaromyces cerevisiae |
Recent history of pneumonia requiring hospitalization | Left cerebellar lesion on imaging | Brain tissue | Positive | Blastomyces dermatitidis |
Heart transplantation | Cavitary pneumonia | BAL | Negative | Rhizopus microsporus |
Renal transplantation | Multiloculted cystic lesion medial to transplanted kidney in left pelvis | Blood | Negative | Histoplasma capsulatum |
Hydrocephalus with a ventriculoperitoneal shunt | Brain lesion | Brain tissue | Positive | Rhodotorula spp. |
Renal transplantation | Cavitary lung lesions/pulmonary nodule | CSF | Negative | Aspergillus |
AML | Pneumonia, sinusitis and periorbital cellulitis | Ethmoid | Negative | Fusarium spp. |
Stage III Wilms tumor | Skin lesion | Scalp lesion | Positive | Rhizopus spp. |
AML | Cutaneous fungal lesions | Skin biopsy | Positive | Fusarium spp. |
Pregnancy | Severe amniotic fluid infection | Placenta tissue | Positive | Candida glabrata |
AML | Neutropenic fevers and pulmonary nodules | Tissue | Negative | Aspergillus spp. |
AML | Disseminated fungal infection with empyema, pericarditis | Pericardial abscess | Positive | Candida tropicalis |
Renal transplantation | Pulmonary cavitary lesion | TISC-left upper lobe region | Negative | Cunningmahella spp. |
No significant medical history | Liver abscess | Liver biopsy | Positive | Candida lusitaniae |
Renal transplantation | Disseminated invasive Aspergillosis involving multiple organs | Brain tissue | Positive | Aspergillus spp. |
Renal transplantation | Mass in the left sinus invading the orbit | Eye tissue | Negative | Aspergillus spp. |