From: Altered cytokine profiles in relapsed paucibacillary leprosy: a case report
IFN-γ (pg/ml) | TNF (pg/ml) | IL-2 (pg/ml) | IL-4 (pg/ml) | IL-6 (pg/ml) | IL-10 (pg/ml) | IFN-γ/IL-10 | TNF/IL-10 | |
---|---|---|---|---|---|---|---|---|
(a) Cytokine profiles of relapsed PB leprosy in the culture supernatants with no stimulus | ||||||||
Before treatment (relapse) | 6.54 | 3.22 | ND | ND | 36.47 | 1.33 | 4.91 | 2.42 |
Six months later | 2.08 | 2.89 | ND | ND | 75.25 | 1.37 | 1.52 | 2.11 |
One year later | 1.07 | 2.96 | ND | ND | 99.86 | 0.92 | 1.16 | 3.22 |
(b) Cytokine profiles of relapsed PB leprosy in the culture supernatants with MLS (8 μg/ml) | ||||||||
Before treatment (relapse) | 125.16 | 41.10 | ND | ND | 17,086.13 | ND | N/A | N/A |
Six months later | 33.07 | 15.70 | ND | ND | 13,839.20 | 0.15 | 220.47 | 104.67 |
One year later | 6.04 | 11.92 | ND | ND | 16,093.10 | ND | N/A | N/A |
(c) Cytokine profiles of relapsed PB leprosy in the culture supernatants with PHA (2.5 μg/ml) | ||||||||
Before treatment (relapse) | 2915.0 | 328.3 | ND | ND | 18,270.9 | 4.3 | 676.3 | 76.2 |
Six months later | 16.5 | 218.3 | ND | ND | 17,867.8 | 5.1 | 3.2 | 42.5 |
One year later | 312.5 | 137.5 | ND | ND | 18,001.2 | 4.1 | 76.4 | 33.6 |