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Table 2 Genotypic and allelic frequencies of the TNFA -308G>A and IL10 -1082A>G polymorphisms in the study groups

From: TNFA -308G>A and IL10 -1082A>G polymorphisms seem to be predictive biomarkers of chronic HCV infection

Allelic or genotypic profile

HCV

n (%)

CG

n (%)

p

TNFA -308G>A

 GG

82 (81.2)

222 (74)

0.0477*

 GA

19 (18.8)

69 (23)

 

 AA

0 (0)

9 (3)

 

 *G

0.91

0.86

0.3753**

 *A

0.09

0.14

 

IL10 -1082A > G

 AA

62 (61.4)

164 (54.7)

0.4847**

 AG

32 (31.7)

109 (36.3)

 

 GG

7 (6.9)

27 (9)

 

 *A

0.77

0.73

0.6242**

 *G

0.23

0.27

 
  1. HCV: patients with chronic hepatitis C; CG: control group
  2. *G-test
  3. **Chi-squared test