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Table 22 Decision to start antibiotic therapy (and which one) based on initial inflammatory parameters

From: Inadequate use of antibiotics in the covid-19 era: effectiveness of antibiotic therapy

On admission

Beta-lactams

Macrolides

Quinolones

No (Total)

N. (%)

No (Total)

N. (%)

No (Total)

N. (%)

Anemia (Hb < 12 g/dL)

2368

1737 (73.4)

2364

1339 (56.6)

2346

330 (14.1)

Thrombocytosis (Platelet count > 180)

7627

5462 (71.6)

7619

4709 (61.8)

7556

977 (12.9)

Leukocytosis (Leukocytes > 10,000

2098

1602 (76.4)

2094

1222 (58.4)

2084

317 (15.2)

Leukopenia (Leukocytes < 4000)

1903

1333 (70.1)

1901

1114 (58.6)

1884

275 (14.6)

Lymphopenia (Lymphocytes < 1300)

10,500

7832 (74.6)

10,492

6432 (61.30)

10,412

1445 (13.9)

C-reactive protein > 50 mg/L

7214

5653 (78.4)

7212

4557 (63.2)

7154

1012 (14.2)

Procalcitonin > 0.5 ng/mL

776

651 (83.9)

774

445 (57.5)

768

110 (14.3)

Ferritin > 274 mcg/L

4118

3021 (73.4)

4117

2869 (69.7)

4099

390 (9.5)

Fibrinogen > 650 mg/dL

3749

2856 (76.2)

3751

2162 (57.6)

3720

432 (11.6)

CK > 200 U/L

1459

1151 (78.9)

1454

927 (63.8)

1444

199 (13.8)

LDH > 300 U/L

6647

5052 (76.0)

6641

4381 (66.0)

6588

824 (12.5)

IL-6 > 4.3 pg/mL

1563

1160 (74.2)

1564

1111 (71.0)

1556

110 (7.1)

D-dimer > 250 ng/mL

9313

6652 (71.4)

9318

6032 (64.7)

9247

1158 (12.5)