Table 5 Antibiotic resistance levels of gam-negative bacteria isolated from septic neonates admitted to referral hospitals in Sana’a city, Yemen, in the period from January 15 to March 30, 2020
From: Neonatal sepsis in Sana’a city, Yemen: a predominance of Burkholderia cepacia
Pathogen | Ampicillin sulbactam | Ampicillin | Amo/CA | Piperacillin/tazobactam | Cefalotin | Cefazolin | Cefuroxime | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | % | N | % | N | % | N | % | N | % | N | % | N | % | |
B. cepacia | 54 | 100 | 60 | 100 | 28 | 100 | 60 | 15 | 27 | 100 | 60 | 100 | 28 | 100 |
K. oxytoca | 20 | 100 | 20 | 100 | 3 | 100 | 20 | 100 | 3 | 100 | 20 | 100 | 3 | 100 |
P. agglomerans | NA | NA | NA | NA | 9 | 100 | 9 | 100 | 9 | 100 | 10 | 100 | 9 | 100 |
P. aeruginosa | 6 | 100 | 6 | 100 | 4 | 100 | 6 | 0 | 4 | 100 | 6 | 100 | 4 | 75 |
K. pneumoniae | 5 | 100 | 5 | 100 | 1 | 100 | 5 | 100 | 1 | 100 | 5 | 100 | 1 | 100 |
P. dispersa | NA | NA | NA | NA | NA | NA | 4 | 100 | NA | NA | 4 | 75 | NA | NA |
A. baumannii | 3 | 33 | 1 | 100 | 3 | 33 | 3 | 33 | 1 | 100 | 3 | 100 | 1 | 100 |
A. lwoffii | 3 | 100 | 3 | 100 | 2 | 100 | 3 | 33 | 3 | 100 | 3 | 100 | 2 | 100 |
E. cloacae complex | NA | NA | NA | NA | 1 | 100 | 3 | 33 | 1 | 100 | 3 | 100 | 1 | 100 |
E. coli | 2 | 50 | 2 | 100 | NA | NA | 2 | 100 | NA | NA | 2 | 100 | NA | NA |
A. denitrificans | 1 | 0 | 1 | 100 | 1 | 0 | 1 | 0 | 1 | 100 | 1 | 100 | 1 | 100 |
S. marcescens | NA | NA | NA | NA | NA | NA | 1 | 100 | NA | NA | 1 | 100 | NA | NA |
S. paucimobilis | 1 | 100 | 1 | 100 | NA | NA | 1 | 100 | NA | NA | 1 | 100 | NA | NA |
Pathogen | Cefuroxime axetil | Cefoxitin | Cefpodoxime | Ceftazidime | Ceftriaxone | Cefepime | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | % | N | % | N | % | N | % | N | % | N | % | |
B. cepacia | 28 | 100 | 59 | 100 | 28 | 100 | 60 | 3.3 | 60 | 10 | 60 | 0 |
K. oxytoca | 3 | 100 | 20 | 100 | 3 | 100 | 20 | 100 | 20 | 100 | 20 | 100 |
P. agglomerans | 9 | 100 | 10 | 100 | 9 | 100 | 10 | 100 | 10 | 100 | 10 | 100 |
P.aeruginosa | 4 | 100 | 6 | 100 | 4 | 75 | 6 | 0 | 6 | 66 | 6 | 0 |
K. pneumoniae | 1 | 100 | 5 | 80 | 1 | 100 | 5 | 100 | 5 | 100 | 5 | 100 |
P. dispersa | NA | NA | 4 | 75 | NA | NA | 4 | 75 | 4 | 75 | 4 | 75 |
A. baumannii | 1 | 100 | 3 | 100 | 1 | 100 | 3 | 100 | 3 | 100 | 3 | 33 |
A. lwoffii | 2 | 100 | 3 | 100 | 2 | 100 | 3 | 33 | 3 | 0 | 3 | 0 |
E. cloacae complex | 1 | 100 | 3 | 100 | 1 | 100 | 3 | 33 | 3 | 33 | 3 | 33 |
E. coli | NA | NA | 2 | 50 | NA | NA | 2 | 100 | 2 | 100 | 2 | 100 |
A. denitrificans | 1 | 100 | 1 | 100 | 1 | 100 | 1 | 0 | 1 | 100 | 1 | 0 |
S. marcescens | NA | NA | 1 | 0 | NA | NA | 1 | 100 | 1 | 100 | 1 | 100 |
S. paucimobilis | NA | NA | 1 | 100 | NA | NA | 1 | 0 | 1 | 100 | 1 | 0 |
Pathogen | Gentamicin | Tobramycin | Ciprofloxacin | Levofloxacin | Tetracycline | FT | SXT | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | % | N | %) | N | % | N | % | N | % | N | % | N | % | |
B. cepacia | 59 | 100 | 60 | 100 | 60 | 98 | 60 | 80 | 28 | 100 | 60 | 100 | 60 | 5 |
K. oxytoca | 20 | 0 | 20 | 100 | 20 | 0 | 20 | 0 | 3 | 0 | 20 | 0 | 20 | 0 |
P. agglomerans | 10 | 100 | 10 | 100 | 10 | 0 | 10 | 0 | 9 | 0 | 10 | 100 | 10 | 0 |
P. aeruginosa | 6 | 66 | 6 | 66 | 6 | 17 | 6 | 33 | 4 | 100 | 6 | 100 | 6 | 66 |
K. pneumoniae | 5 | 20 | 5 | 100 | 5 | 0 | 5 | 0 | 1 | 0 | 5 | 20 | 5 | 40 |
P. dispersa | 4 | 100 | 4 | 100 | 4 | 25 | 4 | 0 | NA | NA | 4 | 75 | 3 | 33 |
A. baumannii | 3 | 66 | 3 | 66 | 3 | 33 | 3 | 33 | 1 | 0 | 3 | 100 | 3 | 100 |
A. lwoffii | 3 | 100 | 3 | 100 | 3 | 0 | 3 | 66 | 2 | 100 | 3 | 100 | 3 | 66 |
E. cloacae complex | 3 | 33 | 3 | 33 | 3 | 33 | 3 | 0 | 1 | 0 | 3 | 33 | 3 | 33 |
E. coli | 2 | 0 | 2 | 50 | 2 | 50 | 2 | 50 | NA | NA | 2 | 0 | 2 | 0 |
A. denitrificans | 1 | 100 | 1 | 100 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 100 | 1 | 0 |
S. marcescens | 1 | 100 | 1 | 100 | 1 | 0 | 1 | 0 | NA | NA | 1 | 100 | 1 | 0 |
S. paucimobilis | 1 | 100 | 1 | 100 | 1 | 0 | 1 | 100 | NA | NA | 1 | 100 | 1 | 0 |
Pathogen | Imipenem | Ertapenem | Meropenem | Amikacin | ESBL | Carbapenemase | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | % | N | % | N | % | N | % | N | % | N | % | |
B. cepacia | 7 | 100 | NA | NA | 53 | 13 | 53 | 100 | – | – | NA | NA |
K. oxytoca | 1 | 100 | 20 | 100 | 20 | 100 | 20 | 65 | 20 | 100 | 20 | 100 |
P. agglomerans | 7 | 100 | 8 | 100 | 10 | 100 | 10 | 100 | 10 | 100 | 10 | 100 |
P. aeruginosa | 2 | 100 | NA | NA | 6 | 0 | 6 | 66 | – | – | – | |
K. pneumoniae | NA | NA | 5 | 80 | 5 | 80 | 5 | 40 | 5 | 100 | 5 | 80 |
P. dispersa | NA | NA | 4 | 50 | 4 | 50 | 4 | 25 | 4 | 75 | 4 | 50 |
A. baumannii | 1 | 0 | NA | NA | NA | NA | NA | NA | 3 | 100 | NA | NA |
A. lwoffii | NA | NA | NA | NA | 1 | 100 | 3 | 100 | – | – | – | |
E. cloacae complex | NA | NA | 3 | 33 | 3 | 33 | 3 | 33 | 3 | 33 | 1 | Pos |
E. coli | NA | NA | 2 | 0 | 2 | 0 | 2 | 0 | 2 | 100 | – | – |
A. denitrificans | 1 | 0 | NA | NA | 1 | 0 | 1 | 100 | 1 | Pos | – | – |
S. marcescens | NA | NA | 1 | 0 | 1 | 0 | 1 | 0 | 1 | Pos | – | – |
S. paucimobilis | NA | NA | NA | NA | 1 | 100 | 1 | 100 | – | Pos | Pos | |