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Table 2 Relationship between the frequency of abnormal clinical/laboratory indices and presence versus absence of RPI, and pattern of RPI (left versus right versus both kidneys, and unilateral versus bilateral

From: Demographic, clinical, and laboratory factors associated with renal parenchymal injury in Iranian children with acute pyelonephritis

Demographic/clinical factora DMSA scansb p-value DMSA scansb p-value DMSA scansb p-value
RPI
(Abnormal, n = 43)
No RPI (Normal, n = 24) RPI in LKCs
(n = 14)
RPI in RKCs
(n = 12)
RPI in both (n = 17) Unilateral
(n = 26) RPI
Bilateral
(n = 17) RPI
BMI (kg/m2) 24 (55.8) 7 (29.2) 0.038* 6 (42.8) 6 (50) 12 (70.6) 0.033* 12 (46.1) 12 (70.6) 0.029*
Fever duration (BT) 12 (27.9) 5 (25) 0.051 4 (28.6) 3 (25) 5 (29.4) 0.662 7 (26.9) 5 (29.4) 0.711
Fever duration (AT) 3 (7) 1 (4.1) 0.754 1 (7.1) 1 (8.3) 1 (5.9) 0.546 2 (7.7) 1 (5.9) 0.684
ESR (mm/h) 7 (16.3) 3 (12.5) 0.125 2 (14.3) 2 (16.7) 3 (17.6) 0.607 4 (15.4) 3 (17.6) 0.655
CRP (mg/L) 2 (4.7) 1 (4.2) 0.711 1 (7.14) 0 (0) 1 (5.9) 0.094 1 (3.8) 1 (5.9) 0.102
WBC (× 109/L) 7 (16.3) 4 (16.7) 0.803 2 (14.3) 2 (16.7) 3 (17.6) 0.607 4 (15.4) 3 (17.6) 0. 655
Hb (g/dL) 3 (7) 2 (8.3) 0.072 1 (7.1) 1 (8.3) 1 (5.9) 0.546 2 (7.7) 1 (5.9) 0.684
BUN (mg/dL) 6 (14) 4 (16.7) 0.314 2 (14.3) 2 (16.7) 2 (11.8) 0.056 4 (15.4) 2 (11.8) 0.052
SCr (mg/dL) 10 (23.3) 3 (12.5) 0.042* 2 (14.3) 4 (33.3) 4 (23.5) 0.039* 8 (30.7) 4 (23.5) 0.045*
eGFR (mL/min/1.73 m2) 4 (9.3) 2 (8.3) 0.772 1 (7.1) 1 (8.3) 1 (5.9) 0.546 2 (7.7) 1 (5.9) 0.684
Anemia (Hb < 10.5 g/dL, %) 11 (25.6) 3 (12) 0.035* 6 (42.8) 2 (16.6) 3 (17.6) 0.036* 8 (30.8) 3 (17.6) 0.040*
  1. Frequencies are expressed as number (percentage)
  2. * p-values less than 0.05 are statistically significant
  3. aBMI body mass index, BT/AT before/after treatment, ESR erythrocyte sedimentation rate, CRP C-reactive protein, WBC white blood cell, Hb hemoglobin, BUN blood urea nitrogen, SCr serum creatinine, eGFR estimated glomerular filtration rate
  4. bRPI renal parenchymal injury, LKCs left kidney changes, RKCs right kidney changes