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Table 5 Presenting symptoms of the dengue patients in 2019 outbreak with comparison of previous outbreak

From: Comparison of clinical manifestation of dengue fever in Bangladesh: an observation over a decade

 

Outbreak

2008

Outbreak

2016

Outbreak

2018

Outbreak

2019

Chi-square statistic

p value*

Lead author

Arif et al. [20]

Pervin et al. [21]

Sultana et al. [22]

Current study

  

Sample size

55

40

350

553

  

Mean age (years)

  

25

27

  

Sex: (%)

      

 Male

83.63

62.5

68.57

63.2

7.1892

0.0073β

 Female

16.37

37.5

31.43

36.8

Clinical features (%)

      

 Fever

 

100

100

100

  

Pain pattern

      

 Headache

32.72

25

61.14

62.7

32.0649

 < 0.0001α

 Myalgia/body ache

 

12.5

44

   

 Low back pain

  

3.14

10.5

  

 Retro-orbital pain/eye ache

16.38

50

20.29

39.1

3.4292

0.0641£

 Arthralgia/joint pain

9.09

87.5

23.14

4.5

14.2545

0.0002β

 Neck pain

   

7.1

  

Respiratory symptoms

  

 Respiratory distress

   

4.5

  

 Cough

   

5.4

  

 Abdominal symptoms

      

 Anorexia

5.45

27.5

 

38

29.3381

 < 0.0001α

 Nausea

 

27.5

 

69.6

  

 Vomiting

40

27.5

    

 Diarrhoea

3.63

25

5.14

26.2

8.9826

0.0027α

Abdominal distension

      

Abdominal pain

1.81

30

32.86

41.6

143.39

 < 0.001α

Clinical signs

      

 Pleural effusion

   

2.5

  

 Ascites

   

1.8

  

 Jaundice

 

12.5

 

1

  

 Skin rash

 

12.5

6

4.5

4.5205

0.0335β

Diff. types of hemorrhagic manifestation

  

 Positive tourniquet test

43.63

  

10.5

  

 Melena

 

7.5

6.1

5.4

0.3717

0.5421

 Gum bleeding

   

3.6

  

 Haematuria

   

0.5

  

 Conj. Hge./hemorrhagic sclera

16.36

20

 

12.1

0.6699

0.4131

 Haematemesis

      

 Haemoptysis

      

 Epistaxis

   

1.6

  

 Vaginal bleeding

   

1.8

  

Others

   

2.4

  

 Less urine output

   

0.2

  

 Hypotension

70.9

  

25

  

 Convulsion

      

 Joint swelling

      

 Lethargy

 

30

    
  1. Statistical analysis was performed for those variables who had data at least for 3 outbreak
  2. *p-value was estimated by using Cochran–Armitage-test and p-value < 0.05 was considered statistically significant
  3. αIncreasing and statistically significant trend present
  4. βDecreasing and statistically significant trend present
  5. £Increasing and statistically non-significant trend present
  6. Decreasing and statistically non-significant trend present