From: Comparison of clinical manifestation of dengue fever in Bangladesh: an observation over a decade
Outbreak 2008 | Outbreak 2016 | Outbreak 2018 | Outbreak 2019 | Chi-square statistic | p value* | |
---|---|---|---|---|---|---|
Lead author | Arif et al. [20] | Pervin et al. [21] | Sultana et al. [22] | Current study | ||
Sample size | 55 | 40 | 350 | 553 | ||
Mean age (years) | 25 | 27 | ||||
Sex: (%) | ||||||
Male | 83.63 | 62.5 | 68.57 | 63.2 | 7.1892 | 0.0073β |
Female | 16.37 | 37.5 | 31.43 | 36.8 | ||
Clinical features (%) | ||||||
Fever | 100 | 100 | 100 | |||
Pain pattern | ||||||
Headache | 32.72 | 25 | 61.14 | 62.7 | 32.0649 | < 0.0001α |
Myalgia/body ache | 12.5 | 44 | ||||
Low back pain | 3.14 | 10.5 | ||||
Retro-orbital pain/eye ache | 16.38 | 50 | 20.29 | 39.1 | 3.4292 | 0.0641£ |
Arthralgia/joint pain | 9.09 | 87.5 | 23.14 | 4.5 | 14.2545 | 0.0002β |
Neck pain | 7.1 | |||||
Respiratory symptoms | ||||||
Respiratory distress | 4.5 | |||||
Cough | 5.4 | |||||
Abdominal symptoms | ||||||
Anorexia | 5.45 | 27.5 | 38 | 29.3381 | < 0.0001α | |
Nausea | 27.5 | 69.6 | ||||
Vomiting | 40 | 27.5 | ||||
Diarrhoea | 3.63 | 25 | 5.14 | 26.2 | 8.9826 | 0.0027α |
Abdominal distension | ||||||
Abdominal pain | 1.81 | 30 | 32.86 | 41.6 | 143.39 | < 0.001α |
Clinical signs | ||||||
Pleural effusion | 2.5 | |||||
Ascites | 1.8 | |||||
Jaundice | 12.5 | 1 | ||||
Skin rash | 12.5 | 6 | 4.5 | 4.5205 | 0.0335β | |
Diff. types of hemorrhagic manifestation | ||||||
Positive tourniquet test | 43.63 | 10.5 | ||||
Melena | 7.5 | 6.1 | 5.4 | 0.3717 | 0.5421€ | |
Gum bleeding | 3.6 | |||||
Haematuria | 0.5 | |||||
Conj. Hge./hemorrhagic sclera | 16.36 | 20 | 12.1 | 0.6699 | 0.4131€ | |
Haematemesis | ||||||
Haemoptysis | ||||||
Epistaxis | 1.6 | |||||
Vaginal bleeding | 1.8 | |||||
Others | 2.4 | |||||
Less urine output | 0.2 | |||||
Hypotension | 70.9 | 25 | ||||
Convulsion | ||||||
Joint swelling | ||||||
Lethargy | 30 |