From: Invasive pneumococcal disease burden in hospitalized adults in Bogota, Colombia
Admission physiological variables. Mean (SD)+ | All patients (n = 310) | Pneumonia (n = 186) | Meningitis (n = 58) | Others (n = 66) |
---|---|---|---|---|
Heart rate, bpm | 97 (24) | 99 (25) | 97 (21) | 94 (26) |
Systolic blood pressure, mmHg | 117 (26.3) | 114 (26) | 123 (26) | 117 (24) |
Diastolic blood pressure, mmHg | 70 (16) | 68 (17) | 72 (14) | 71 (16) |
MAP, mmHg | 84 (22) | 81 (23) | 88 (17.6) | 85 (21) |
Respiratory rate, rpm | 21 (5) | 21 (5) | 20 (6) | 20 (5) |
Oximetry, % | 88 (12) | 87 (11) | 92 (4) | 87 (18) |
Glasgow scale | 14 (3) | 14 (2.2) | 12 (3) | 14 (5) |
Temperature, °C | 36.92 (1.98) | 37.05 (1.03) | 37.26 (1.89) | 36.24 (3.48) |
Full blood count | ||||
Leukocytes, ×109/L | 13.26 (8.91) | 12.44 (8.77) | 16.62 (8.61) | 12.54 (9.01) |
Neutrophils, 109/L* | 10 (5.2–16.4) | 8.6 (4.2–15.85) | 13.3 (8.22–21.45) | 9.3 (5.09–15.00) |
Hemoglobin, g/dL | 12.9 (3.4) | 12.52 (3.01) | 14.13 (2.52) | 13.02 (4.77) |
Hematocrit, % | 42.15 (40.25) | 40.09 (29.96) | 42.75 (7.82) | 47.42 (71.13) |
Platelets, ×103* | 201 (141–271) | 209 (159–284.5) | 188 (127.25–271.5) | 179.5 (105.50–248.75) |
Glucose, mg/dL* | 119 (94–156) | 119 (94–146.5) | 131 (98.5–167) | 114 (83.25–162.50) |
Urea nitrogen, mg/dL* | 21.9 (15–39.8) | 23.8 (17–42) | 17 (11–25.47) | 20 (12.00–41.00) |
Creatinine, mg/dL* | 1.06 (0.7–1.7) | 1.14 (0.79–1.81) | 0.9 (0.7–1.2) | 0.9 (0.70–2.12) |
Sodium concentration, mmol/L | 133 (20.43) | 133 (19.18) | 131.64 (24.74) | 133.73 (19.97) |
Potassium concentration, mmol/L* | 3.9 (3.5–4.4) | 3.9 (3.57–4.5) | 3.7 (3.3–4.2) | 4.1 (3.60–4.60) |
Bilirubin levels | ||||
Total bilirubin, mg/dL* | 1.1 (0.6–2.2) | 1.09 (0.58–1.9) | 1.03 (0.52–2.23) | 1.27 (0.63–3.34) |
Direct bilirubin, mg/dL* | 0.55 (0.3–1.14) | 0.55 (0.29–1.12) | 0.73 (0.2–1.15) | 0.51 (0.30–1.36) |
Indirect bilirubin, mg/dL* | 0.5 (0.2–1.0) | 0.45 (0.22–0.9) | 0.47 (0.21–1.1) | 0.57 (0.30–1.35) |
Liver enzymes | ||||
AST, UI/L* | 39 (24–79) | 36 (22.95–66.75) | 28 (17–111) | 47 (28.75–83.05) |
ALT, UI/L* | 36.2 (21–83.6) | 35 (20–83.67) | 37.4 (21–91) | 43 (24.00–84.00) |
Arterial blood gases | ||||
pH* | 7.42 (7.34–7.47) | 7.4 (7.33–7.46) | 7.44 (7.35–7.48) | 7.43 (7.36–7.48) |
PO2, mmHg | 70.43 (36.16) | 66.88 (38.71) | 81 (35) | 72.29 (22.33) |
PCO2, mmHg | 29.9 (12.59) | 30.33 (10.82) | 27.29 (8.18) | 30.99 (20) |
FiO2, % | 30 (18) | 30 (18) | 33 (23) | 25 (11) |
HCO3, meq/L* | 18 (14.47–20.65) | 18 (14.5–21) | 17 (14.2–19.5) | 17 (14.62–20.27) |
Lactate, mmol/L* | 2.8 (1.9–4.82) | 2.8 (1.9–5.3) | 2.7 (1.77–3.82) | 2.75 (1.62–4.57) |
CRP, mg/L* | 32 (15.29–133) | 36 (15–165.9) | 47 (20–193) | 24 (13.05–38.90) |
Procalcitonin | 26 (56.79) | 30.11 (67.29) | 20.66 (36.81) | 18.49 (36.23) |
PT | 15.63 (6.77) | 14.86 (5.21) | 16.84 (7.71) | 16.21 (8.49) |
PTT | 34.49 (−19.51) | 34 (9.44) | 32.19 (11.64) | 37.08 (33.96) |
Clinical severity scores (IQR) | All patients | Pneumonia | Meningitis | Others |
---|---|---|---|---|
qSOFA | 1 (0–2) | 1 (0–2) | 1 (0–2) | 1 (1–2) |
SOFA | 5 (3–8) | 5 (3–8) | 5 (3–9) | 5 (3–8) |
APACHE II | 13 (11–19) | 15 (11–20) | 13 (7–15) | 12 (9–20) |