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Table 2 Univariate analysis between severe and mild infections

From: Predictors of severe leptospirosis: a multicentre observational study from Central Malaysia

Variables Severe cases (n = 33, 39.8%) Mild cases (n = 50,
60.2%)
Odds ratio 95% CI χ2 test Corrected X2 tailed p
p < 0.05
Gender M:F (70%, M) (62%, M) 1.4 0.6–3.6 0.2 0.6
Older age > 60 years 27% 22% 1.3 0.4–4.1 0.08 0.7
Fever 97% 98% 0.7 0.008–52.8 UN 1#
Headache 30% 48% 0.5 0.2–1.2 1.9 0.2
GIT involvement 55% 70% 0.5 0.2–1.3 1.4 0.2
Myalgia 36% 30% 1.3 0.5–3.4 0.1 0.7
Mechanical ventilation 18% 0% UN UN UN 0.0029**#
AKI 48% 8% 10.8 2.9–49.2 15.7 0.00007**
Septic shock 21% 4% 6.5 1.1–66.6 4.4 0.035**
Creatinine > 1.13 mg/dL 70% 24% 7.3 2.7–19.5 15.2 0.00009**
Urea > 7 mmol/L 67% 22% 7.1 2.6–19.0 14.7 0.0001**
Bilirubin > 32.49 μmol 33% 18% 2.2 0.7–7.1 1.7 0.2
ALT > 50 IU 58% 32% 2.9 1.2–7.2 4.3 0.037**
AST > 50 IU 79% 40% 5.7 2.1–15.6 10.6 0.001**
HCT < 35% 56% 42% 1.8 0.7–4.4 1.1 0.3
Platelet < 150 × 109/L 58% 22% 4.8 1.8–12.6 9.4 0.002**
HB < 11.5 g/dL 48% 38% 1.5 0.6–3.7 0.5 0.5
WBC < 11 × 109/L 42% 40% 1.1 0.5–2.7 0.0 1
Leptospira interrogans 68% 71% 0.9 0.2–3.3 0.0 1
Leptospira kirschneri 32% 26% 1.4 0.3–5.1 0.04 0.8
  1. UN undefined
  2. #p-value based on Fisher-exact test
  3. **Significant value