| |
Pulmonary N = 198 (%)
|
Extrapulmonary N = 57 (%)
|
P value
|
|---|
|
Site
|
|
Only skin
|
–
|
1/57 (1.8)
| |
|
Only bloodstream
|
–
|
5/57 (8.8)
| |
|
Only CNS
|
–
|
42/57 (73.7)
| |
|
Bloodstream and CNS
|
–
|
9/57 (15.8)
| |
|
Laboratory test indicators
|
|
LY (*109/L)
|
2.0 ± 0.8
|
1.0 ± 0.9
|
< 0.001
|
|
CSF CrAg (meningitis)
|
–
|
44/45 (97.8)
| |
|
Serum CrAg
|
105/132 (79.5)
|
23/23 (100.0)
|
0.015
|
|
Symptom
|
|
Asymptomatic
|
54 (27.3)
|
5 (8.8)
|
0.005
|
|
Fever
|
28 (14.1)
|
43 (75.4)
|
< 0.001
|
|
Headache/dizziness
|
6 (3.0)
|
45 (79.0)
|
< 0.001
|
|
Meningeal irritation
|
0
|
6 (10.5)
|
< 0.001
|
|
Medical history
|
|
Mild-to-moderate immunodeficiency
|
34 (17.2)
|
9 (15.9)
|
0.806
|
|
Severe immunodeficiency
|
1246 (6.1)
|
3140 (54.4)
|
< 0.001
|
|
Glucocorticoid
|
17 (8.6)
|
25 (43.9)
|
< 0.001
|
|
Immunosuppressants
|
10 (5.1)
|
21 (36.8)
|
< 0.001
|
|
Autoimmune-related diseases
|
6 (3.0)
|
12 (21.1)
|
< 0.001
|
|
Kidney transplant
|
4 (2.0)
|
9 (15.8)
|
< 0.001
|
|
AIDS
|
1 (0.5)
|
7 (10.5)
|
< 0.001
|
|
Diabetes
|
20 (10.1)
|
5 (8.7)
|
0.766
|
|
APACHE II, median (IQR)
|
2.0 (1.0, 5.0)
|
7.0 (3.5, 10.8)
|
< 0.001
|
- CNS, central nervous system; LY, lymphocyte
