Skip to main content

Table 1 Demographic data and medical history of cryptococcosis patients with different immune statuses

From: Clinical features of cryptococcosis in patients with different immune statuses: a multicenter study in Jiangsu Province–China

  Total N = 255 (%) IC N = 169 (%) MID N = 43 (%) SID N = 43 (%) P value
Demographic data
 Sex (male) 160 (62.7) 113 (66.9) 24 (54.5) 23 (54.8) 0.162
 Age (y) 46.6 ± 13.7 46.4 ± 12.8 51.8 ± 14.4 41.9 ± 14.9  < 0.001 (#)
 BMI, kg/m2 23.3 ± 3.3 23.8 ± 3.0 24.3 ± 3.4 20.2 ± 2.4  < 0.001 (*)
 Contact history 16 (6.3) 12 (7.1) 3 (7.0) 1 (2.3) 0.504
 Time since diagnosis(d) 30.0 (14.3, 60.0) 30.0 (15.0, 60.0) 30.0 (22.0, 60.0) 17.5 (9.0, 30.0)  < 0.001 (*)
 Dissemination 57 (22.4) 17 (10.1) 8 (18.6) 32 (74.4)  < 0.001 (*)
Medical history
 Diabetes 13 (6.4) 8 (14.6) 0.06 25 (9.8) 0 20 (46.5) 5 (11.6)  
 Glucocorticoid 38 (69.1) 42 (16.5) 0 11 (25.6) 31 (72.1)  
 Liver dysfunction 11 (4.3) 0 8 (18.6) 3 (7.0)  
 Chemotherapy 05 (9.1) 6 (2.4) 0 6 (14.0) 0  
 Autoimmune diseases 0 27 (49.1) 18 (7.1) 0 6 (14.0) 12 (27.9)  
 Other renal disease 1 (0.5) 4 (7.3) 8 (3.1) 0 2 (4.7) 6 (14.0)  
 Haemopathy 6 (2.4) 0 1 (2.3) 5 (11.2)  
 AIDS 08 (14.6) 8 (3.1) 0 0 8 (18.6)  
 Kidney transplant 013 (23.6) 13 (5.1) 0 0 13 (30.2)  
 Immunosuppressant 31 (12.2) 0 0 31 (72.1)  
  1. Haemopathy included myelodysplastic syndrome (MDS, n = 2), allergic purpura (n = 1), multiple myeloma (MM, n = 1), lymphoma (n = 1), and haemolytic anaemia (HA, n = 1); Autoimmune diseases included systemic lupus erythematosus (SLE, n = 10), rheumatoid arthritis (RA, n = 3), connective tissue disease (CTD, n = 1), sarcoidosis (n = 1), ankylosing spondylitis (AS, n = 1), Hashimoto thyroiditis (HT, n = 1), and pemphigoid (n = 1); Other renal diseases included nephrotic syndrome (NS, n = 6), IgA nephropathy (IgAN, n = 1), and renal cell carcinoma (RCC, n = 1); Liver dysfunction included hepatic cirrhosis (n = 9) and hepatocellular carcinoma (HCC, n = 2)
  2. BMI, body mass index; *SID vs. IC/MID; #MID vs. IC/SID;