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Table 1 Demographic data and medical history of cryptococcosis patients with different immune statuses

From: Clinical features of cryptococcosis in patients with different immune statuses: a multicenter study in Jiangsu Province–China

 

Total N = 255 (%)

IC N = 169 (%)

MID N = 43 (%)

SID N = 43 (%)

P value

Demographic data

 Sex (male)

160 (62.7)

113 (66.9)

24 (54.5)

23 (54.8)

0.162

 Age (y)

46.6 ± 13.7

46.4 ± 12.8

51.8 ± 14.4

41.9 ± 14.9

 < 0.001 (#)

 BMI, kg/m2

23.3 ± 3.3

23.8 ± 3.0

24.3 ± 3.4

20.2 ± 2.4

 < 0.001 (*)

 Contact history

16 (6.3)

12 (7.1)

3 (7.0)

1 (2.3)

0.504

 Time since diagnosis(d)

30.0 (14.3, 60.0)

30.0 (15.0, 60.0)

30.0 (22.0, 60.0)

17.5 (9.0, 30.0)

 < 0.001 (*)

 Dissemination

57 (22.4)

17 (10.1)

8 (18.6)

32 (74.4)

 < 0.001 (*)

Medical history

 Diabetes 13 (6.4) 8 (14.6) 0.06

25 (9.8)

0

20 (46.5)

5 (11.6)

 

 Glucocorticoid 38 (69.1)

42 (16.5)

0

11 (25.6)

31 (72.1)

 

 Liver dysfunction

11 (4.3)

0

8 (18.6)

3 (7.0)

 

 Chemotherapy 05 (9.1)

6 (2.4)

0

6 (14.0)

0

 

 Autoimmune diseases 0 27 (49.1)

18 (7.1)

0

6 (14.0)

12 (27.9)

 

 Other renal disease 1 (0.5) 4 (7.3)

8 (3.1)

0

2 (4.7)

6 (14.0)

 

 Haemopathy

6 (2.4)

0

1 (2.3)

5 (11.2)

 

 AIDS 08 (14.6)

8 (3.1)

0

0

8 (18.6)

 

 Kidney transplant 013 (23.6)

13 (5.1)

0

0

13 (30.2)

 

 Immunosuppressant

31 (12.2)

0

0

31 (72.1)

 
  1. Haemopathy included myelodysplastic syndrome (MDS, n = 2), allergic purpura (n = 1), multiple myeloma (MM, n = 1), lymphoma (n = 1), and haemolytic anaemia (HA, n = 1); Autoimmune diseases included systemic lupus erythematosus (SLE, n = 10), rheumatoid arthritis (RA, n = 3), connective tissue disease (CTD, n = 1), sarcoidosis (n = 1), ankylosing spondylitis (AS, n = 1), Hashimoto thyroiditis (HT, n = 1), and pemphigoid (n = 1); Other renal diseases included nephrotic syndrome (NS, n = 6), IgA nephropathy (IgAN, n = 1), and renal cell carcinoma (RCC, n = 1); Liver dysfunction included hepatic cirrhosis (n = 9) and hepatocellular carcinoma (HCC, n = 2)
  2. BMI, body mass index; *SID vs. IC/MID; #MID vs. IC/SID;