- List of amino acid changes in the non-structural protein of the GII.2[P16] recombinant strain compared with those of previous GII.P16 NoV. Asterisks denote residue deletion in the P48 protein of GII.P16 noroviruses. The sequences of P48, NTPase, 3A protein, VPg, Pro and RdRp were aligned. Motif G is one of the conserved segments of RdRp according to function and structure, and the 1310 position belongs to Motif G. The negative results are not shown