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Table 1 Demographic, clinical, and laboratory findings for patients with brucellosis at the time of sample collection

From: Impact of immune checkpoint molecules on FoxP3+ Treg cells and related cytokines in patients with acute and chronic brucellosis

Variable Acute patients, no. (%)
n = 40
Chronic patients, no. (%)
n = 19
Sex
 Male 32 (80.0) 16 (84.2)
 Female 8 (20.0) 3 (15.8)
Age (years)
 18–30 5 (12.5) 0 (0)
 31–45 13 (32.5) 4 (21.1)
 46–60 17 (42.5) 11 (57.9)
 61–70 5 (12.5) 4 (21.1)
Area
 Urban area 4 (10.0) 0 (0)
 Rural area 36 (90.0) 19 (100)
Transmission mechanisms
 Direct contact with infected sheep 37 (92.5) 15 (78.9)
 Ingesting undercooked mutton 3 (7.5) 4 (21.1)
Signs and symptoms
 Fever (> 37.3 °C) 37 (92.5) 10 (52.6)
 Sweating 37 (92.5) 9 (47.4)
 Constitutional symptomsa 28 (70.0) 17 (89.5)
 Hepatomegaly or splenomegaly 5 (12.5) 2 (10.5)
 Myalgia or arthralgia 26 (65.0) 17 (89.5)
 Lumbar pain 9 (22.5) 14 (73.7)
 Epididymoorchitis 2 (5.0) 0 (0)
 Respiratory disorders 3 (7.5) 0 (0)
Laboratory findings
 Hematologic
  WBC > ULN (3.97–9.15) × 109/L] 6 (15.0) 5 (26.3)
  NEU-R > ULN [(50–70)%] 16 (40.0) 7 (36.8)
 Transaminasemia
  ALT > ULN [40 U/L] 16 (40.0) 9 (47.4)
  AST > ULN [40 U/L] 11 (27.5) 6 (31.6)
 CRP > 5 mg/L 35 (87.5) 15 (78.9)
 ESRb 34 (85.0) 14 (73.7)
 Disease duration
  Less than 14 days 14 (35.0)
  Between 15 and 30 days 23 (57.5)
  Between 31 and 60 days 3 (7.5)
  Between 6 and 9 months   8 (42.1)
  Between 9 and 12 months   6 (31.6)
  Between 12 and 15 months   5 (26.3)
  1. ULN Upper limit of normal
  2. aConstitutional symptoms comprise anorexia, malaise, asthenia, weight loss
  3. bESR: Male > 15 mm/h, Female > 20 mm/h