Skip to main content

Table 1 Demographic, clinical, and laboratory findings for patients with brucellosis at the time of sample collection

From: Impact of immune checkpoint molecules on FoxP3+ Treg cells and related cytokines in patients with acute and chronic brucellosis

Variable

Acute patients, no. (%)

n = 40

Chronic patients, no. (%)

n = 19

Sex

 Male

32 (80.0)

16 (84.2)

 Female

8 (20.0)

3 (15.8)

Age (years)

 18–30

5 (12.5)

0 (0)

 31–45

13 (32.5)

4 (21.1)

 46–60

17 (42.5)

11 (57.9)

 61–70

5 (12.5)

4 (21.1)

Area

 Urban area

4 (10.0)

0 (0)

 Rural area

36 (90.0)

19 (100)

Transmission mechanisms

 Direct contact with infected sheep

37 (92.5)

15 (78.9)

 Ingesting undercooked mutton

3 (7.5)

4 (21.1)

Signs and symptoms

 Fever (> 37.3 °C)

37 (92.5)

10 (52.6)

 Sweating

37 (92.5)

9 (47.4)

 Constitutional symptomsa

28 (70.0)

17 (89.5)

 Hepatomegaly or splenomegaly

5 (12.5)

2 (10.5)

 Myalgia or arthralgia

26 (65.0)

17 (89.5)

 Lumbar pain

9 (22.5)

14 (73.7)

 Epididymoorchitis

2 (5.0)

0 (0)

 Respiratory disorders

3 (7.5)

0 (0)

Laboratory findings

 Hematologic

  WBC > ULN (3.97–9.15) × 109/L]

6 (15.0)

5 (26.3)

  NEU-R > ULN [(50–70)%]

16 (40.0)

7 (36.8)

 Transaminasemia

  ALT > ULN [40 U/L]

16 (40.0)

9 (47.4)

  AST > ULN [40 U/L]

11 (27.5)

6 (31.6)

 CRP > 5 mg/L

35 (87.5)

15 (78.9)

 ESRb

34 (85.0)

14 (73.7)

 Disease duration

  Less than 14 days

14 (35.0)

–

  Between 15 and 30 days

23 (57.5)

–

  Between 31 and 60 days

3 (7.5)

–

  Between 6 and 9 months

 

8 (42.1)

  Between 9 and 12 months

 

6 (31.6)

  Between 12 and 15 months

 

5 (26.3)

  1. ULN Upper limit of normal
  2. aConstitutional symptoms comprise anorexia, malaise, asthenia, weight loss
  3. bESR: Male > 15 mm/h, Female > 20 mm/h