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Table 2 Factors associated with viral suppression (n = 831)

From: Viral suppression among HIV-positive patients on antiretroviral therapy in northwestern Nigeria: an eleven-year review of tertiary care centre records, January 2009–December 2019

Variables

n (%)

Viral load suppressed n = 751

Viral load unsuppressed n = 80

P value

Baseline CD4 counts (cells/µl) *

  < 500

404 (48.6)

346 (46.1)

58 (72.5)

 < 0.001

  ≥ 500

427 (51.4)

405 (53.9)

22 (27.5)

 

Years on HAART

  < 5 years

354 (42.6)

325 (43.3)

29 (36.3)

0.237

  ≥ 5 years

477 (57.4)

426 (56.7)

51 (63.7)

 

HAART Regimen

 First Line

793 (95.4)

728 (96.9)

65 (81.3)

 < 0.001

 Second Line

38 (4.6)

23 (3.1)

15 (18.7)

 

TB confirmed**

 Yes

21 (2.5)

19 (2.8)

2 (2.8)

1.000f

 No

731 (88.0)

662 (97.2)

69 (97.2)

 

 Missing

79 (9.5)

   

Disease stage

 WHO stages 1 and 2

809 (97.4)

732 (97.5)

77 (96.3)

0.461f

 WHO stages 3 and 4

22 (2.6)

19 (2.5)

3 (3.7)

 

Pregnancy Status (n = 578)

 Not Pregnant

558 (96.5)

501 (96.7)

57 (95.0)

0.452f

 Pregnant

20 (3.5)

17 (3.3)

3 (5.0)

 

Viral Load (cp/ml)

Median (IQR)

20 (20–74)

Range (20 to 2,469,613)

20 (20–40)

Range (20 to 925)

19,989 (3311 to 110,340)

Range (1170 to 2,468,443.0)

 < 0.001

2019

Viral Load (cp/ml)

Median (IQR)

20 (20–70.5)

Range (20 to 2,469,613)

N = 744

20 (20–40)

Range (20 to 845)

N = 674

17,086.5 (3228.8–131,695

Range (1170 to 2,469,613)

N = 70

 < 0.001

2018

Viral Load (cp/ml)

Median (IQR)

20 (20–119)

Range (20 to 112,454)

N = 87

20 (20–39.5)

Range (20 to 925)

N = 77

31,997.0

(4205.5–68,372.0)

Range (1373 to 112,454)

N = 10

 < 0.001

  1. *Baseline value of CD4 count at enrollment (Prior to the commencement of anti-retroviral therapy-ART); **TB confirmed cases among those with viral load suppression; IQR-Interquartile range; f-Fischer exact test