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Table 3 Comparison of culture and LAMP method results on 161 urine samples

From: LAMP assays for the simple and rapid detection of clinically important urinary pathogens including the detection of resistance to 3rd generation cephalosporins

LAMP Culture Sensitivity Specificity PPV NPV K
Positive Negative % [95% CI] % [95% CI] % [95% CI] % [95% CI]  
E. coli        
Positive 23 (TP) 2 (FP) 95.8 98.5 92 99.3 0.93
Negative 1 (FN) 135 (TN) [78.9–99.9] [94.8–99.8] [74.4–97.9] [95.2–99.9]  
K. pneumoniae        
Positive 6 (TP) 8 (FP) 100 94.8 42.9 100 0.58
Negative 0 (FN) 147 (VN) [54.07–100] [90.1–97.7] [27.6–59.6]  
P. mirabilis        
Positive 3 (TP) 0 (FP) 100 100 100 100 1
Negative 0 (FN) 158 (TN) [29.2–100] [97.7–100]  
E. faecalis        
Positive 2 (TP) 2 (FP) 100 98.7 50 100 0.66
Negative 0 (FN) 157 (TN) [15.8–100] [95.5–99.8] [20.1–79.8]  
CTX-M groupe 1        
Positive 11 (TP) 0 (FP) 100 100 100 100 1
Negative 0 (FN) 150 (TN) [71.5–100] [97.6–100]  
  1. CI, Confidence Interval; TP, true positive, FP, false positive; TN, true negative; FN, false negative; PPV, positive predictive value; NPV, negative predictive value; K, Cohen’s Kappa