From: Efficacy and safety of polymyxin B in carbapenem-resistant gram-negative organisms infections
Group | n | Effective rate (n (%)) | P-value | Clearance rate (n (%)) | P-value |
---|---|---|---|---|---|
Infection types | |||||
Pneumonia | 104 (44.2) | 46 (44.2%) | 0.395 | 35 (33.7%) | 0.387 |
Bloodstream infection | 36 (44.2) | 13 (36.1%) | 15 (41.7%) | ||
Prognosis | |||||
Survival | 74 (44.2) | 71 (95.9%) | ≤ 0.001 | 56 (75.7%) | ≤ 0.001 |
Death | 107 (44.2) | 19 (17.8%) | 20 (18.7%) | ||
Time from carbapenem resistance to PB use (h) | |||||
< 24 | 55 (44.2) | 33 (60.0%) | 0.008 | 30 (54.5%) | 0.016 |
> 24 | 93 (44.2) | 35 (37.6%) | 32 (34.4%) |