Table 3 Summary of antimicrobial susceptibility in the previously reported human cases with Enterococcus hirae

1

ABPC, VCM, IPM GM

N/A

No beta-lactamase activity

2

N/A

N/A

3

N/A

N/A

4

ABPC, VCM, TEIC, CP

CLDM, EM, RFP, TC

Low-level resistance to SM, KM, GM

5

N/A

N/A

6

N/A

N/A

7

N/A

N/A

8

N/A

N/A

9

N/A

N/A

10

ABPC, PCG, CP, CPFX, OFLX, LVFX, TC, VCM

CLDM, NFLX

No evidence of high-level aminoglycoside resistance to GM or SM

Intermediate susceptibility to EM, NTF

11

N/A

N/A

12

N/A

N/A

13

N/A

CLDM, Cephalosporins

14

EM, CP, LZD, VCM

RFP

Intermediate susceptibility to ABPC, DOXY

15

ABPC, TEIC, VCM, high dose GM

OFLX, GM

16

ABPC, TEIC, VCM, high dose GM

OFLX, GM

17

ABPC, MFLX, VCM, TEIC, EM, RFP

CLDM, FOS

Low-level resistance to SM, KM, GM

18

ABPC, VCM, TEIC, EM, TC

high-level SM and GM

N/A

19

AMPC

Cephalosporins

20

N/A

N/A

21

ABPC, VCM, TEIC, LZD, TC

CPFX

No high-level resistance to GM

22

ABPC, VCM, CPFX

N/A

23

high-level GM and KM, ABPC, LZD, CPFX, Nitrofuran, VCM

ST

24

AMPC/CVA, PIPC/TAZ

CXM-AX, NTF

25

VCM

N/A

26

ABPC, ABPC/SBT, CPFX, EM, high-level GM, IPM, LVFX, LZD, NFLX, PCG, QPR/DPR, high-level SM, TEIC, TC, VCM, TGC

none

intermediate susceptibility to NTF

27

ABPC, ABPC/SBT, CPFX, EM, high-level GM, IPM, LVFX, LZD, NFLX, PCG, QPR/DPR, high-level SM, TEIC, TC, VCM, TGC

none

intermediate susceptibility to NTF

28

N/A

N/A

29

ABPC, IPM, GM, CPFX, LVFX, VCM, TEIC, ST, LZD, TGC

N/A

30

ABPC, AMPC, VCM

N/A

It demonstrated synergy with GM and SM

31

ABPC, VCM, high-level GM

N/A

32

ABPC, PCG, VCM, LVFX, TEIC, LZD

none