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Table 4 AUC, Youden’s index and accuracy results of single parameters with statistical significance between medians of malaria positive, malaria negative, and dengue positive samples

From: The utility of basic blood counts, WBC histogram and C-reactive protein in detecting malaria

Parameter

Malaria vs Negative samples

Malaria vs dengue samples

AUC

Cut-off value at YI

Sens.%

Spe. %

Odds ratio (CI 95%)

AUC

Cut-off value at YI

Sens.%

Spe. %

Odds ratio (CI 95%)

WBC

0.672

 ≤ 5.75

(103/µL)

62.71%

66.94%

3.40 (2.33–4.97)

0.580

 ≥ 4.35

(\({10}^{3}\)/µL)

65.94%

47.10%

1.72 (1.06–2.80)

MCHC

0.613

 ≥ 33.95

(g/dL)

39.83%

80.42%

2.71 (1.79–4.11)

0.620

 ≥ 33.85

(g/dL)

44.20%

78.26%

2.85 (1.68–4.82)

RDW

0.558

 ≤ 13.85

(%)

28.39%

86.44%

2.52 (1.58–4.03)

    

PLT

0.849

 ≤ 161.5

(103/µL)

86.44%

75.00%

19.12 (11.89–30.75)

0.780

 ≤ 160.5

(103/µL)

88.40%

58.69%

10.83 (5.81–20.17)

%LYM

    

0.628

 ≥ 24.6

(%)

63.76%

59.12%

2.54 (1.56–4.14)

CRP

0.852

 ≥ 27.65

(mg/L)

84.74%

71.36%

13.84 (8.79–21.80)

0.867

 ≥ 26.85

(mg/L)

84.78%

73.91%

15.78 (8.66–28.76)

  1. The sensitivity, specificity, and odds ratios were calculated with the cut-off values of the Youden’s index. Negative samples were matched with malaria positive samples in age and sex