Impact of a hospital-wide computerised approach to optimise the quality of antimicrobial prescriptions in patients with severe obesity: a quasi-experimental study

Table 3 Recommendations in patients with class III obesity

	No. approved	No. rejected	Total	Acceptation rate (%)	Frequency (%)
Posology	424	24	455	93.2	46.1
Switch from IV to oral therapy	91	12	105	86.7	10.6
Discontinuation of treatment	78	1	79	98.7	8.0
Duration	70	1	71	98.6	7.2
Microbiology	66	3	70	94.3	7.1
Missing dosage target	39	0	39	100	4.0
Interaction	38	0	38	100	3.9
Off target serum concentration	23	0	23	100	2.3
Restricted antimicrobials	21	0	21	100	2.1
Other^a	77	7	86	90.0	8.7
Total	927	48	987^b	93.9	100

^aLess than 2%: cost (n = 18), individualized intervention (n = 12), renal toxicity (n = 10), laboratory test request (n = 9), prolonged infusion (n = 9), antimicrobial associated with C. difficile risk (n = 6), spectrum redundancy (n = 6), allergy (n = 4), post hemodialysis dose (n = 4), asymptomatic bacteriuria (n = 3), exception (n = 3), antiviral after negative testing (n = 2)
^bUnknown acceptance status in 12 interventions

ISSN: 1471-2334