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Table 3 Recommendations in patients with class III obesity

From: Impact of a hospital-wide computerised approach to optimise the quality of antimicrobial prescriptions in patients with severe obesity: a quasi-experimental study

  No. approved No. rejected Total Acceptation rate (%) Frequency (%)
Posology 424 24 455 93.2 46.1
Switch from IV to oral therapy 91 12 105 86.7 10.6
Discontinuation of treatment 78 1 79 98.7 8.0
Duration 70 1 71 98.6 7.2
Microbiology 66 3 70 94.3 7.1
Missing dosage target 39 0 39 100 4.0
Interaction 38 0 38 100 3.9
Off target serum concentration 23 0 23 100 2.3
Restricted antimicrobials 21 0 21 100 2.1
Othera 77 7 86 90.0 8.7
Total 927 48 987b 93.9 100
  1. aLess than 2%: cost (n = 18), individualized intervention (n = 12), renal toxicity (n = 10), laboratory test request (n = 9), prolonged infusion (n = 9), antimicrobial associated with C. difficile risk (n = 6), spectrum redundancy (n = 6), allergy (n = 4), post hemodialysis dose (n = 4), asymptomatic bacteriuria (n = 3), exception (n = 3), antiviral after negative testing (n = 2)
  2. bUnknown acceptance status in 12 interventions