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Table 2 Investigations on day 1 and day 4 following NAC treatment

From: Use of intravenous N-acetylcysteine in acute severe hepatitis due to severe dengue infection: a case series

 

Day 1

Day 4

p

Hemoglobin g/L

125 ± 14.8

126 ± 14.8

 

HCT %

40.07 ± 6.8

37.58 ± 2.57

 

WBC × 109/L

3.65 ± 1.26

6.31 ± 1.98

 

Platelets × 109/L

32.04 ± 28.09

57. 28 ± 54.32

0.011

INR

1.28 ± 0.17

1.14 ± 0.26

0.115

AST U/L

1125 (IQR 1653.25)

870 (IQR 1136.25)

0.049

ALT U/L

752 (IQR 459.25)

548 (IQR 762.00)

0.034

AST/ALT

1.859 (IQR 0.76)

2.042 (IQR 1.02)

0.711

  1. Values for haemoglobin WBC HCT and INR are given as mean ± standard deviation. AST ALT AST/ALT are given as median with IQR indicated in brackets
  2. Day 1 and Day 4 represents stating day and day 4 of NAC treatment respectively
  3. p value indicates the difference of values between day 1 and day 4
  4. HCT haematocrit; WBC white cell count; ALT alanine transaminase; AST aspartate transaminases; PT INR prothrombin time and international normalized ratio IQR interquartile range