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Table 1 Clinical signs and symptoms of different aetiologies in patients with a sore throat, number (%) if not otherwise stated

From: The aetiology of pharyngotonsillitis in primary health care: a prospective observational study

 

Mutually exclusive groups

 

Clinical signs and symptoms

Total

n = 220

Only viruses

n = 52

Only bacteria

n = 85

Viruses + bacteria

n = 18

No pathogen

n = 65

GAS

n = 66

Any bacteria

n = 103

Age (years), median (IQR)

33 (23–39)

28 (21–38)

34 (24–40)

35 (26–38)

32 (23–40)

36 (33–40)

34 (26–39)

Female

141/220 (64)

34 (65)a

58 (68)a

8 (44)

41 (63)a

43 (65)

66 (64)

Smoker

30/215 (14)

7 (13)a

11 (13)a

2 (11)

10 (15)a

5 (8)

13 (13)

Days with symptoms, median (IQR)

4 (3–7)

4 (3–7)

3 (3–5)

3 (3–4)

6 (3–10)

3 (3–4)

3 (3–5)

Longstanding sore throat before inclusion

69/215 (32)

15 (29)a

22 (26)a

4 (22)

28 (43)a

16 (24)

26 (25)

Frequent sore throats

72/216 (33)

24 (46)a,

24 (28)a

6 (33)

18 (28)a

18 (27)

30 (29)

Tonsillectomised

29/219 (13)

8 (15)a

11 (13)a

2 (11)

8 (12)a

11 (17)

13 (13)

Antibiotics last month

17/216 (8)

6 (12)a

7 (8)a

0 (0)

4 (6)a

3 (5)

7 (7)

Coryza

89/220 (40)

35 (67)†††

20 (24)

7 (39)

27 (42)

12 (18)

27 (26)

Cough

88/220 (40)

35 (67)†††

18 (21)

9 (50)

26 (40)

12 (18)

27 (26)

Temperature ≥ 38.5 °C

128/215 (60)

32 (62)a

56 (66)a

13 (72)

27 (42)a

48 (73)

69 (67)

Lymphadenitis

130/215 (60)

32 (62)a

56 (66)a

10 (56)

32 (49)a

44 (67)

66 (64)

Tonsillar coating

84/207 (41)

15 (29)a,††

45 (53)a

7 (39)

17 (26)a

36 (55)

52 (50)

Palatal petechiae

25/207 (12)

9 (17)

10 (12)

3 (17)

3 (5)

8 (12)

13 (13)

Duration ≤ 3 days

96/213 (45)

21 (40)

43 (51)

10 (56)

22 (34)

36 (55)

53 (51)

Centor 0

16/220 (7)a

5 (10)a

3 (4)a

1 (6)

7 (11)a

2 (3)

4 (4)

Centor 1

50/220 (23)a

14 (27)a

8 (9)a

4 (22)

24 (37)a

6 (9)

12 (12)

Centor 2

69/220 (31)a

20 (38)a

26 (31)a

5 (28)

18 (28)a

16 (24)

31 (30)

Centor 3

54/220 (25)a

10 (19)a

28 (33)a

7 (39)

9 (14)a

24 (36)

35 (34)

Centor 4

31/220 (14)a

3 (6)a

20 (24)a

1 (6)

7 (11)a

18 (27)

21 (20)

Centor 3–4

85/220 (39)

13 (25)†††

48 (56)

8 (44)

16 (25)

42 (64)

56 (54)

  1. GAS group A streptococci
  2. p = 0.03 compared to “only bacteria”
  3. ††p = 0.006 compared to “only bacteria”
  4. †††p < 0.001 compared to “only bacteria”
  5. aThese numbers were previously published by Hedin et al. [14] but are republished here for the sake of completeness