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Table 2 Univariate analysis of potential predictive parameters for ICU admission in hospitalized COVID-19 patients

From: Development and validation of nomogram to predict severe illness requiring intensive care follow up in hospitalized COVID-19 cases

 

Beta

OR

95% CI L

95% CI U

p

Age, 56.5 years and older

2.34

10.34

6.42

17.78

 < 0.0001

Gender. female sex

−0.42

0.66

0.43

1.03

0.0577

Hypertension

1.11

3.04

1.96

4.91

 < 0.0001

Diabetes

1.35

3.84

2.30

6.27

 < 0.0001

Chronic pulmonary disease

1.37

3.95

2.01

6.98

 < 0.0001

Malignity

1.71

5.52

2.04

13.65

0.0004

Coronary arterial disease

1.32

3.73

2.00

6.42

 < 0.0001

Number of comorbidities

0.81

2.24

1.63

3.05

 < 0.0001

Fever on admission

0.59

1.80

1.14

2.75

0.0098

Dyspnea on admission

1.81

6.13

3.87

9.65

 < 0.0001

Oxygen saturation, 94.5% and below

2.67

14.50

8.93

25.80

 < 0.0001

White blood cell, 7.4 × 109/L and above

1.13

3.10

1.83

5.00

 < 0.0001

Monocyte, 0.23 × 109/L and below

1.17

3.23

1.95

5.28

 < 0.0001

NLR, 3.5 and above

1.91

6.74

4.25

11.37

 < 0.0001

Hemoglobin, 12.5 g/L and below

0.96

2.60

1.69

4.02

 < 0.0001

Platelet count, 155 × 109/L and below

0.84

2.32

1.41

3.67

0.0006

Urea, 36.1 mg/dL and above

1.55

4.69

3.06

7.42

 < 0.0001

Creatinine, 0.96 mg/dL and above

0.87

2.38

1.54

3.69

 < 0.0001

GFR, 96.2 ml/min/1.73 m2 and below

1.75

5.78

3.47

9.68

 < 0.0001

Aspartate transaminase, 28.5 U/L and above

2.07

7.92

5.02

13.39

 < 0.0001

Alanine transaminase, 40.5 U/L and above

0.50

1.65

1.02

2.64

0.0369

Albumin, 42.5 g/L and below

2.18

8.83

5.66

15.52

 < 0.0001

Creatine kinase, 141.5 U/L and above

0.92

2.50

1.61

3.85

 < 0.0001

Lactate dehydrogenase, 286.5 U/L and above

2.41

11.17

6.94

18.72

 < 0.0001

C-reactive protein, 0.0275 g/L and above

2.58

13.14

8.42

22.96

 < 0.0001

Procalcitonin, 0.085 pg/mL and above

2.74

15.49

10.19

25.67

 < 0.0001

Troponin, 5.9 ng/L and above

2.52

12.45

7.90

22.09

 < 0.0001

Prothrombin time, 12.5 s and above

1.46

4.31

2.86

6.52

 < 0.0001

aPTT, 26.2 s and above

0.48

1.62

1.05

2.43

0.0230

INR, 1.06 and above

1.42

4.12

2.67

6.54

 < 0.0001

Ferritin, 227.5 µg/L and above

1.74

5.67

3.73

9.13

 < 0.0001

D-dimer, 0.535 mg/L and above

2.28

9.74

5.95

18.92

 < 0.0001

Fibrinogen, 3.40 g/L and above

1.57

4.81

3.10

7.94

 < 0.0001

Bilateral infiltration on CT

1.43

4.20

2.68

7.33

 < 0.0001

qSOFA:1

2.67

14.49

9.38

22.95

 < 0.0001

qSOFA:2

3.26

25.92

15.96

36.14

 < 0.0001

  1. NLR, Neutrophil to lymphocyte ratio; aPTT, Activated partial thromboplastin time; INR, International normalized ratio; CT, Computed tomography; GFR, Glomerular filtration rate; qSOFA, quick sequential organ failure assessment
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BMC Infectious Diseases

ISSN: 1471-2334

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