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Table 1 Patient’s laboratory parameters

From: First description of immune complex vasculitis after COVID-19 vaccination with BNT162b2: a case report

Parameter

2 days before 2nd vaccination

12 days after 2nd vaccination

5 days later on prednisolone

Normal range

Blood results

 CRP (mg/dl)

2.09

8.69

 

< 0.50

 Creatinine (mg/dl)

0.82

0.97

1.43

0.70–1.20

 Albumin (g/dl)

3.5

3.5

3.1

3.5–5.2

 Total bilirubin (mg/dl)

1.0

1.4

0.7

< 1.4

 Direct bilirubin /mg/dl)

 

0.8

0.4

< 0.3

 ASAT (U/l)

47

36

51

< 40

 ALAT (U/l)

38

25

37

< 50

 GGT (U/l)

31

44

69

< 50

 LDH (U/l)

205

211

223

< 248

 CK (U/l)

85

108

 

< 190

 Lactate (mg/dl)

 

16.3

 

4.5–20.0

 ESR (mm/h)

 

42

19

< 20

 PCT (ng/ml)

 

0.29

 

< 0.50

 IL-6 (pg/ml)

 

104.0

26.6

< 7.0

 Leucocytes (/nl)

4.57

5.87

6.01

3.92–9.81

 Haemoglobin (g/dl)

11.6

11.3

10.1

13.5–17.5

 Platelets (/nl)

141

114

133

146–328

 INR

1.19

1.23

1.26

0.85–1.27

 IgG (mg/dl)

1567

1549

1364

700–1600

 C3c (mg/dl)

  

87

90–180

 C4 (mg/dl)

  

16.1

10.0–40.0

 ANA

 

1:80

 

< 1:80

 c-ANCA (IFT)

 

Negative

 

Negative

 p-ANCA (IFT)

 

Negative

 

Negative

 c-ANCA (PR3) EILSA

 

Negative

 

Negative

 p-ANCA (MPO) ELISA

 

Negative

 

Negative

Urine results

 Leukocytes (/µl)

 

350

447

< 10

 Erythrocytes (/µl)

 

11

30

< 5

Stool results

    

 Calprotectin (µg/g)

 

115

 

< 50

 EDN (ng/ml)

 

802

 

< 1700

 iFOBT

 

Positive

 

Negative

 Stool pathogens

 

Negative

  

Virology

 CMV-DNA

 

Negative

  

 EBV-DNA

 

Negative

  

 HSV-1 IgG

 

positive 17.1 index

  

 HSV-2 IgG

 

Negative

  

 HHV-6 IgG

 

Negative

  

 HHV-6 IgM

 

Negative

  

 VZV IgG

 

Positive 2727 mE/ml

  

 VZV IgM

 

Negative

  

 Parvovirus B19 IgG

 

Positive 10 index

  

 Parvovirus B19 IgM

 

Negative

  

Microbiology

 Treponema pallidum screening

 

Negative

  

 Mycoplasma pneumoniae IgG

 

Negative

  

 Mycoplasma pneumoniae IgM

 

Negative

  
  1. Newly elevated laboratory results and dynamics are presented in bold
  2. CRP c-reactive-protein, ASAT aspartate transferase, ALAT alanine transferase, GGT gamma glutamyl transferase, LDH lactate dehydrogenase, CK creatinine kinase, ESR erythrocyte sedimentation rate, PCT procalcitonin, IL interleukin, INR international normalized ratio, IgG immunoglobulin G, C3C complement component 3, C4 complement component 4, ANA antinuclear antibody, ANCA antinuclear cytoplasm antibody, EDN eosinophil-derived antitoxin, iFOBT immunochemical faecal occult blood test, CMV cytomegalovirus, DNA desoxyribonucleic acid, Ig immunoglobulin, EBV Ebstein-Barr-virus, HSV herpes simplex virus, HHV human herpes virus, VZV varicella zoster virus