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Table 3 Microbial constituents in PLA between cohorts

From: Epidemiology and risk factors for pyogenic liver abscess in the Calgary Health Zone revisited: a population-based study

Factor 1999–2003 Cohort 2015–2017 Cohort p value
Polymicrobial 35/71 (49%) 44/136 (32%) 0.01
Nosocomial PLA 6/71 (9%) 6/136 (4.4%) 0.19
Streptococcus anginosus group 31/71 54/136 0.34
Klebsiella species 19/71 34/136 0.45
Anaerobesa 14/71 22/136 0.32
Escherichia coli 11/71 24/136 0.43
Enterococcus species 5/71 12/136 0.44
Staphylococcus aureus 4/71 2/136 0.11
Other bacteria 11/71 26/136 0.33
Culture negativeb 12/71 13/136 0.10
Antimicrobial resistant isolate present 1/71 11/136 0.04
  1. aAnaerobes included Clostridium perfringens, Bacteroides species, Peptostreptococcus species, Fusobacterium species, Actinomyces species, Prevotella species, Lactobacillus species, Veillonella species. The prevalence of these organisms was not different between the two cohorts
  2. bPatients classified as culture negative had negative blood and aspiration cultures (4/136) or negative blood cultures only when aspiration was not performed (9/136)