Table 2 Population-based factors associated with increased risk of PLA
Underlying condition | Number of patients (n = 136) | Estimated number with underlying condition at riska | Incidence Rate per 100,000b | RR (95% CI) | p value |
|---|---|---|---|---|---|
Diabetes | 33 | 281,890 | 11.7 | 3.81 (2.58–5.65) | < 0.0001 |
Current malignancy | 26 | 18,931 | 137.3 | 45.13 (29.44–69.18) | < 0.0001 |
Ischemic heart disease | 19 | 135,675 | 14.00 | 4.19 (2.58–6.81) | < 0.0001 |
Chronic obstructive pulmonary disease | 10 | 84,285 | 11.86 | 3.35 (1.76–6.37) | 0.001 |
Cirrhosis | 6 | 8,975 | 66.85 | 18.65 (8.23–42.27) | < 0.0001 |
Congestive heart failure | 5 | 53,851 | 9.28 | 2.54 (1.04–6.21) | 0.05 |
End stage renal disease | 4 | 3,999 | 100.02 | 27.51 (10.18–74.36) | < 0.0001 |
Liver transplant | 4 | 2,643 | 151.34 | 41.63 (15.40–112.47) | < 0.0001 |