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Table 2 Population-based factors associated with increased risk of PLA

From: Epidemiology and risk factors for pyogenic liver abscess in the Calgary Health Zone revisited: a population-based study

Underlying condition Number of patients (n = 136) Estimated number with underlying condition at riska Incidence Rate per 100,000b RR (95% CI) p value
Diabetes 33 281,890 11.7 3.81 (2.58–5.65)  < 0.0001
Current malignancy 26 18,931 137.3 45.13 (29.44–69.18)  < 0.0001
Ischemic heart disease 19 135,675 14.00 4.19 (2.58–6.81)  < 0.0001
Chronic obstructive pulmonary disease 10 84,285 11.86 3.35 (1.76–6.37) 0.001
Cirrhosis 6 8,975 66.85 18.65 (8.23–42.27)  < 0.0001
Congestive heart failure 5 53,851 9.28 2.54 (1.04–6.21) 0.05
End stage renal disease 4 3,999 100.02 27.51 (10.18–74.36)  < 0.0001
Liver transplant 4 2,643 151.34 41.63 (15.40–112.47)  < 0.0001
  1. aEstimated 3 year prevalence of the underlying condition in the CHZ
  2. bIncidence rate of PLA among those with the underlying condition