|
Etiology
|
Prevalence between 1999 and 2003
|
Prevalence between 2015 and 2017
|
p-value
|
|---|
|
Cryptogenic
|
56% (40/71)
|
29% (40/136)
|
< 0.001
|
|
Biliary
|
24% (17/71)
|
34% (46/136)
|
0.09
|
|
Choledocholithiasis
|
7% (5/71)
|
7% (10/136)
|
0.59
|
|
Cholecystitis
|
7% (5/71)
|
15% (20/136)
|
0.08
|
|
Ascending cholangitis
|
6% (4/71)
|
11% (15/136)
|
0.15
|
|
Common bile duct stricture
|
4% (3/71)
|
4% (5/136)
|
0.56
|
|
Pylephlebitis
|
1% (1/71)
|
10% (14/136)
|
0.01
|
|
Cholangiocarcinoma
|
1% (1/71)
|
4% (6/136)
|
0.24
|
|
Bile leak post-cholecystectomy
|
1% (1/71)
|
1% (2/136)
|
0.73
|
|
Choledochojejunostomy
|
1% (1/71)
|
0% (0/136)
|
0.34
|
|
Nonbiliary
|
20% (14/71)
|
36% (49/136)
|
0.01
|
|
Neutropenia
|
4% (3/71)
|
1% (1/136)
|
0.12
|
|
Perforation
|
3% (2/71)
|
4% (5/136)
|
0.55
|
|
Pneumonia/empyema
|
3% (2/71)
|
0% (0/136)
|
0.12
|
|
Diverticulitis
|
1% (1/71)
|
12% (16/136)
|
0.006
|
|
Perinephric abscess
|
1% (1/71)
|
0% (0/136)
|
0.34
|
|
Endocarditis
|
1% (1/71)
|
0% (0/136)
|
0.34
|
|
Dental abscess
|
1% (1/71)
|
1% (1/136)
|
0.57
|
|
Appendicitis
|
1% (1/71)
|
1% (2/136)
|
0.73
|
|
Traumatic liver injury
|
1% (1/71)
|
1% (1/136)
|
0.57
|
|
Gastroenteritis/colitis
|
0% (0/71)
|
5% (7/136)
|
0.05
|
|
Post-surgical complication
|
0% (0/71)
|
3% (4/136)
|
0.18
|
|
Superinfected liver metastasis
|
0% (0/71)
|
2% (3/136)
|
0.28
|
|
Pancreatitis
|
0% (0/71)
|
1% (2/136)
|
0.43
|
|
Othera
|
0% (0/71)
|
1% (2/136)
|
0.43
|
- aOcclusion of colonic sinus tract, pharyngitis
