Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high risk

BMC Infectious Diseases

Table 2 Predictors of symptomatic laboratory-confirmed SARS-COV-2 reinfection, Mexico 2020

	RR (95% CI), p
	Bivariate analysis			Multiple analysis
Gender
Female	1.0000			1.0000
Male	0.9998	(0.9993–1.0004)	0.574	1.0004	(0.9997–1.0009)	0.256
Age group (years)
20–49	1.0000			1.0000
50–59	0.9987	(0.9980–0.9995)	0.001	0.9989	(0.9981–0.9997)	0.006
60–69	0.9984	(0.9973–0.9996)	0.007	0.9984	(0.9972–0.9996)	0.009
70 +	0.9983	(0.9968–0.9999)	0.039	0.9982	(0.9966–0.9999)	0.032
Occupation
Housewife	1.0000			1.0000
Healthcare worker	1.0043	(1.0032–1.0054)	< 0.001	1.0042	(1.0030–1.0055)	< 0.001
Other healthcare-related	1.0026	(1.0013–1.0038)	< 0.001	1.0025	(1.0012–1.0039)	< 0.001
Student	0.9994	(0.9964–1.0025)	0.721	0.9993	(0.9961–1.0024)	0.646
Other	1.0006	(0.9996–1.0015)	0.227	1.0005	(0.9994–1.0016)	0.337
Disease severity (at primary infection)^a
Mild-moderate	1.0000			1.0000
Severe	0.9987	(0.9979–0.9994)	< 0.001	0.9989	(0.9981–0.9997)	0.007
Personal history of:
Obesity (BMI 30 or higher)
No	1.0000			1.0000
Yes	0.9996	(0.9988–1.0003)	0.228	0.9997	(0.9989–1.0004)	0.360
Type 2 diabetes mellitus
No	1.0000			1.0000
Yes	0.9993	(0.9984–1.0001)	0.082	0.9996	(0.9987–1.0005)	0.333
Immunosuppression^b
No	1.0000			1.0000
Yes	1.0040	(1.0013–1.0066)	0.003	1.0038	(1.0011–1.0065)	0.005
Chronic kidney disease
No	1.0000			1.0000
Yes	1.0038	(1.0015–1.0061)	0.001	1.0039	(1.0016–1.0063)	0.001

RR Risk ratio, CI Confidence interval, BMI Body mass index
1) Generalized linear regression models were used to obtain RR and 95% CI; 2) Multiple regression coefficients were adjusted by variables listed in the table
^aSevere illness included the register of dyspnea requiring hospital admission
^bImmunosuppression referred to any cause of the related deficiency except for type 2 diabetes mellitus or renal impairment

ISSN: 1471-2334