BMC Infectious Diseases

Table 2 Predictive value of biomarker combinations for neonatal sepsis

From: The potential value of plasma receptor interacting protein 3 in neonates with culture-positive late-onset sepsis

Variable	RIP3 + hs-CRP	RIP3 + PLT	hs-CRP + PLT	RIP3 + hs-CRP + PLT
AUC	0.892	0.859	0.842	0.897
Sensitivity	77.8	69.8	65.1	77.8
Specificity	97.5	94.9	94.9	97.5
PPV	96.1	91.7	91.1	96.1
NPV	84.6	79.8	77.3	84.6
PPR	30.72	13.79	12.85	30.72
NPR	0.23	0.32	0.37	0.23
95%CI	0.829–0.938	0.790–0.911	0.772–0.898	0.835–0.942
YI	0.753	0.648	0.600	0.753

AUC area under the curve, CI confidence interval, PPV positive predictive value, NPV negative predictive value, PPR positive probability ratio, NPR negative probability ratio, YI Youden index

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ISSN: 1471-2334

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