Fig. 5

CD8⁺T cells in AF mothers tend to secrete pro-inflammatory cytokines. A Representative dot plots of the production of cytokines (IFN-γ, IL-21, TNF-α, IL-2, IL-10, and IL-4) in CD8⁺ T cells. B–F Percentages of cytokine-producing CD8⁺ T cells in AF mothers (n = 6) or NAF mothers (n = 14) at 26–28 weeks of gestation, 30–32 weeks of gestation, delivery, 6–8 weeks postpartum, or 15–18 weeks postpartum. G The data represent the ratio of pro-inflammatory cytokine to anti-inflammatory cytokine (IFN-γ:IL-10) in CD8⁺ T cells from 26 to 28 weeks of gestation to 15–18 weeks postpartum. The data represent the median with 95% CI. *P < 0.05, **P < 0.005