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Table 1 Characteristics of Patients in the training and testing Cohorts

From: Machine learning-based CT radiomics model distinguishes COVID-19 from non-COVID-19 pneumonia

Characteristic

Training cohort

Testing cohort

COVID-19

Other types of-pneumonia

P value

COVID-19

Other types of pneumonia

p value

Patients

52

60

–

11

11

–

Exams

206

69

–

38

13

–

Age

52.7 ± 12.6

41.5 ± 15.5

 < 0.001b

47.5 ± 16.1

46.9 ± 18.4

0.942b

Gender, Male (%)

31 (60%)

33 (55%)

0.623a

5 (45%)

8 (73%)

0.387a

Exposure history

  

0.006a

  

0.375a

 Close contact with infected patients

52 (100%)

52(87%)

 

8 (73%)

6 (55%)

 

 Unknown cause

0 (0%)3

8(13%)

 

3 (27%)

5 (45%)

 

Comorbidities, No. (%)

 Cardiovasular disease

1 (2%)

1(2%)

1.000a

2 (18%)

1 (9%)

0.534a

 Diabetes

4 (8%)

0(0%)

0.029a

0 (0%)

0 (0%)

–

 Hypertension, No. (%)

9 (17%)

4(7%)

0.080a

0 (0%)

1 (9%)

0.317a

 COPD

3 (6%)

2(3%)

0.535a

0 (0%)

0 (0%)

–

 Chronic liver disease

2 (4%)

1(2%)

0.478a

0 (0%)

0 (0%)

–

 Chronic kidney disease

0 (0%)

0(0%)

–

0 (0%)

1 (9%)

0.317a

 Cancer, No. (%)

0 (0%)

1(2%)

0.352a

1 (9%)

2 (18%)

0.544a

Symptoms

 Fever, No. (%)

46 (88%)

46 (77%)

0.104a

6 (55%)

7 (64%)

0.672a

 Cough, No. (%)

43 (83%)

26 (43%)

 < 0.001a

6 (55%)

3 (27%)

0.387a

 Myalgia, No. (%)

10 (19%)

2 (3%)

0.007a

2 (18%)

0 (0%)

0.476a

 Fatigue, No. (%)

18 (35%)

2 (3%)

 < 0.001a

0 (0%)

0 (0%)

–

 Headache, No. (%)

9 (17%)

1 (2%)

0.01a

2 (18%)

0 (0%)

0.476a

 Nausea, No. (%)

5 (10%)

0 (0%)

0.046a

2 (18%)

0 (0%)

0.476a

 Diarrhea, No. (%)

7 (13%)

1 (2%)

0.04a

1 (9%)

0 (0%)

1.000a

 Bellyache, No. (%)

0 (0%)

0 (0%)

–

1 (9%)

0 (0%)

1.000a

 Dyspnea, No. (%)

1 (2%)

0 (0%)

0.464a

0 (0%)

0 (0%)

–

 Other symptoms, No. (%)

19 (37%)

14 (23%)

0.126a

4 (36%)

2 (18%)

0.635a

Laboratory results

 White blood cell count

4.8 ± 2.0

8.2 ± 3.5

 < 0.001b

5.1 ± 1.8

9.4 ± 3.4

0.001b

 Number of neutrophils, × 109/L

3.2 ± 1.9

5.8 ± 3.2

 < 0.001b

3.2 ± 1.5

6.8 ± 3.3

0.003b

 Lymphocyte count, × 109/L

1.2 ± 0.8

1.6 ± 1.1

0.032b

1.4 ± 0.5

1.7 ± 1.0

0.473b

 Hemoglobin

134.1 ± 25.2

138.7 ± 17.6

0.267b

128.3 ± 19.8

139.7 ± 21.3

0.206b

 Platelet count, × 109/L

175.8 ± 60.3

225.6 ± 62.0

 < 0.001b

215.6 ± 70.7

230.1 ± 89.0

0.678b

  1. pa chi-square test, pb Student’s t test. pc Kruskal–Wallis H test