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Table 2 Multimorbidity index conditions among participants in the UK Biobank Study

From: Patterns of multimorbidity and risk of severe SARS-CoV-2 infection: an observational study in the U.K.

Multimorbidity index conditions

With severe SARS-CoV-2 infectiona

N = 1706 (0.5%)

Without severe SARS-CoV-2 infectionb

N = 358,577 (99.5%)

P value

Hypertension

676 (39.6)

90,747 (25.3)

 < 0.001

Asthma

226 (13.3)

41,382 (11.5)

0.028

Diabetes

170 (10.0)

14,079 (3.9)

 < 0.001

Cancer

179 (10.5)

27,108 (7.6)

 < 0.001

Angina

111 (6.5)

10,037 (2.8)

 < 0.001

Myocardial infarction

102 (6.0)

7096 (2.0)

 < 0.001

Chronic kidney disease

93 (5.5)

7188 (2.0)

 < 0.001

Stroke

47 (2.8)

3957 (1.1)

 < 0.001

Atrial fibrillation

26 (1.5)

2508 (0.7)

 < 0.001

Chronic obstructive pulmonary disease

14 (0.8)

929 (0.3)

 < 0.001

Heart failure

5 (0.3)

146 (0.04)

 < 0.001

Peripheral vascular disease

4 (0.2)

595 (0.2)

0.488

Number of multimorbidity index conditions

   

 None

683 (40.0)

206,012 (57.5)

 

 One

592 (34.7)

111,153 (31.0)

 

 Two

293 (17.2)

32,059 (8.9)

 

 Three

96 (5.6)

7341 (2.1)

 

 Four

27 (1.6)

1646 (0.5)

 

 Five

12 (0.7)

311 (0.1)

 

 Six

2 (0.1)

47 (0.01)

 

 Seven

1 (0.1)

7 (0.0)

 

 Eight

0 (0.0)

1 (0.0)

 < 0.001

  1. P-values calculated by chi squared test
  2. aSevere SARS-CoV-2 infection included those with a positive test result for SARS-CoV-2 with hospitalisation, or those who died during the study period (16 March to 26 July, 2020)
  3. bThose without severe SARS-CoV-2 infection included those who had not been tested, or who had tested negative for SARS-CoV-2